skip to main content
DOE Patents title logo U.S. Department of Energy
Office of Scientific and Technical Information

Title: Cleavage of nucleic acids

Abstract

The present invention relates to means for the detection and characterization of nucleic acid sequences, as well as variations in nucleic acid sequences. The present invention also relates to methods for forming a nucleic acid cleavage structure on a target sequence and cleaving the nucleic acid cleavage structure in a site-specific manner. The structure-specific nuclease activity of a variety of enzymes is used to cleave the target-dependent cleavage structure, thereby indicating the presence of specific nucleic acid sequences or specific variations thereof.

Inventors:
 [1];  [1];  [1];  [1];  [1]
  1. Madison, WI
Issue Date:
Research Org.:
Third Wave Technologies, Inc. (Madison, WI)
Sponsoring Org.:
USDOE
OSTI Identifier:
921021
Patent Number(s):
7306917
Application Number:
11/222,565
Assignee:
Third Wave Technologies, Inc. (Madison, WI)
Patent Classifications (CPCs):
C - CHEMISTRY C12 - BIOCHEMISTRY C12Q - MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS
Y - NEW / CROSS SECTIONAL TECHNOLOGIES Y10 - TECHNICAL SUBJECTS COVERED BY FORMER USPC Y10S - TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
DOE Contract Number:  
FG02-94ER81891
Resource Type:
Patent
Country of Publication:
United States
Language:
English
Subject:
60 APPLIED LIFE SCIENCES

Citation Formats

Prudent, James R, Hall, Jeff G, Lyamichev, Victor L, Brow, Mary Ann D, and Dahlberg, James E. Cleavage of nucleic acids. United States: N. p., 2007. Web.
Prudent, James R, Hall, Jeff G, Lyamichev, Victor L, Brow, Mary Ann D, & Dahlberg, James E. Cleavage of nucleic acids. United States.
Prudent, James R, Hall, Jeff G, Lyamichev, Victor L, Brow, Mary Ann D, and Dahlberg, James E. Tue . "Cleavage of nucleic acids". United States. https://www.osti.gov/servlets/purl/921021.
@article{osti_921021,
title = {Cleavage of nucleic acids},
author = {Prudent, James R and Hall, Jeff G and Lyamichev, Victor L and Brow, Mary Ann D and Dahlberg, James E},
abstractNote = {The present invention relates to means for the detection and characterization of nucleic acid sequences, as well as variations in nucleic acid sequences. The present invention also relates to methods for forming a nucleic acid cleavage structure on a target sequence and cleaving the nucleic acid cleavage structure in a site-specific manner. The structure-specific nuclease activity of a variety of enzymes is used to cleave the target-dependent cleavage structure, thereby indicating the presence of specific nucleic acid sequences or specific variations thereof.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {2007},
month = {12}
}

Patent:

Save / Share:

Works referenced in this record:

Mass generation from tachyon condensation for vector fields on D-branes
journal, August 2000


The off switch for HP1
journal, November 2005


David William Alexander Johnston
journal, May 2005