skip to main content
DOE Patents title logo U.S. Department of Energy
Office of Scientific and Technical Information

Title: Antifungal polypeptides

Abstract

Compositions and methods for protecting a plant from a pathogen, particularly a fungal pathogen, are provided. Compositions include novel amino acid sequences, and variants and fragments thereof, for antipathogenic polypeptides that were isolated from microbial fermentation broths. Nucleic acid molecules comprising nucleotide sequences that encode the antipathogenic polypeptides of the invention are also provided. A method for inducing pathogen resistance in a plant using the nucleotide sequences disclosed herein is further provided. The method comprises introducing into a plant an expression cassette comprising a promoter operably linked to a nucleotide sequence that encodes an antipathogenic polypeptide of the invention. Compositions comprising an antipathogenic polypeptide or a transformed microorganism comprising a nucleic acid of the invention in combination with a carrier and methods of using these compositions to protect a plant from a pathogen are further provided. Transformed plants, plant cells, seeds, and microorganisms comprising a nucleotide sequence that encodes an antipathogenic polypeptide of the invention, or variant or fragment thereof, are also disclosed.

Inventors:
 [1];  [2];  [3];  [4];  [5];  [6];  [7];  [4];  [8];  [9];  [10];  [11];  [3]
  1. Waukee, IA
  2. Oakland, CA
  3. (Kyiv, IL)
  4. Wilmington, DE
  5. Elliott City, MD
  6. Clive, IA
  7. Avondale, PA
  8. Port Deposit, MD
  9. Des Moines, IA
  10. Richmond, CA
  11. Johnston, IA
Issue Date:
Research Org.:
Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States)
Sponsoring Org.:
USDOE
OSTI Identifier:
921018
Patent Number(s):
7306946
Application Number:
11/174,413
Assignee:
Pioneer Hi-Bred International, Inc. (Johnston, IA); E.I. duPunt de Nemours and Company (Wilmington, DE); The Regents of the University of California (Oakland, CA)
Patent Classifications (CPCs):
C - CHEMISTRY C12 - BIOCHEMISTRY C12N - MICROORGANISMS OR ENZYMES
C - CHEMISTRY C07 - ORGANIC CHEMISTRY C07K - PEPTIDES
DOE Contract Number:  
AC02-05CH11231
Resource Type:
Patent
Country of Publication:
United States
Language:
English

Citation Formats

Altier, Daniel J, Dahlbacka, Glen, Ellanskaya, legal representative, Natalia, Herrmann, Rafael, Hunter-Cevera, Jennie, McCutchen, Billy F, Presnail, James K, Rice, Janet A, Schepers, Eric, Simmons, Carl R, Torok, Tamas, Yalpani, Nasser, and Ellanskaya, deceased, Irina. Antifungal polypeptides. United States: N. p., 2007. Web.
Altier, Daniel J, Dahlbacka, Glen, Ellanskaya, legal representative, Natalia, Herrmann, Rafael, Hunter-Cevera, Jennie, McCutchen, Billy F, Presnail, James K, Rice, Janet A, Schepers, Eric, Simmons, Carl R, Torok, Tamas, Yalpani, Nasser, & Ellanskaya, deceased, Irina. Antifungal polypeptides. United States.
Altier, Daniel J, Dahlbacka, Glen, Ellanskaya, legal representative, Natalia, Herrmann, Rafael, Hunter-Cevera, Jennie, McCutchen, Billy F, Presnail, James K, Rice, Janet A, Schepers, Eric, Simmons, Carl R, Torok, Tamas, Yalpani, Nasser, and Ellanskaya, deceased, Irina. Tue . "Antifungal polypeptides". United States. https://www.osti.gov/servlets/purl/921018.
@article{osti_921018,
title = {Antifungal polypeptides},
author = {Altier, Daniel J and Dahlbacka, Glen and Ellanskaya, legal representative, Natalia and Herrmann, Rafael and Hunter-Cevera, Jennie and McCutchen, Billy F and Presnail, James K and Rice, Janet A and Schepers, Eric and Simmons, Carl R and Torok, Tamas and Yalpani, Nasser and Ellanskaya, deceased, Irina},
abstractNote = {Compositions and methods for protecting a plant from a pathogen, particularly a fungal pathogen, are provided. Compositions include novel amino acid sequences, and variants and fragments thereof, for antipathogenic polypeptides that were isolated from microbial fermentation broths. Nucleic acid molecules comprising nucleotide sequences that encode the antipathogenic polypeptides of the invention are also provided. A method for inducing pathogen resistance in a plant using the nucleotide sequences disclosed herein is further provided. The method comprises introducing into a plant an expression cassette comprising a promoter operably linked to a nucleotide sequence that encodes an antipathogenic polypeptide of the invention. Compositions comprising an antipathogenic polypeptide or a transformed microorganism comprising a nucleic acid of the invention in combination with a carrier and methods of using these compositions to protect a plant from a pathogen are further provided. Transformed plants, plant cells, seeds, and microorganisms comprising a nucleotide sequence that encodes an antipathogenic polypeptide of the invention, or variant or fragment thereof, are also disclosed.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {2007},
month = {12}
}

Patent:

Save / Share:

Works referenced in this record:

Purification, Characterisation and cDNA Cloning of an Antimicrobial Peptide from Macadamia Integrifolia
journal, March 1997


Functional Analysis of Conserved Histidines in ADP-Glucose Pyrophosphorylase from Escherichia coli
journal, March 1998


Transforming growth factor alpha: mutation of aspartic acid 47 and leucine 48 results in different biological activities.
journal, March 1988


In Defense against Pathogens. Both Plant Sentinels and Foot Soldiers Need to Know the Enemy: Fig. 1.
journal, April 2003


Isolation and Characterization of a Novel Antifungal Peptide from Aspergillus niger
journal, October 1999


Functional Domain Analysis of the Yeast ABC Transporter Ycf1p by Site-directed Mutagenesis
journal, August 1999