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Title: Integrated optical biosensor system (IOBS)

Abstract

An optical biosensor has a first enclosure with a pathogen recognition surface, including a planar optical waveguide and grating located in the first enclosure. An aperture is in the first enclosure for insertion of sample to be investigated to a position in close proximity to the pathogen recognition surface. A laser in the first enclosure includes means for aligning and means for modulating the laser, the laser having its light output directed toward said grating. Detection means are located in the first enclosure and in optical communication with the pathogen recognition surface for detecting pathogens after interrogation by the laser light and outputting the detection. Electronic means is located in the first enclosure and receives the detection for processing the detection and outputting information on the detection, and an electrical power supply is located in the first enclosure for supplying power to the laser, the detection means and the electronic means.

Inventors:
 [1];  [1];  [1];  [2];  [1];  [1]
  1. Los Alamos, NM
  2. White Rock, NM
Issue Date:
Research Org.:
Los Alamos National Lab. (LANL), Los Alamos, NM (United States)
Sponsoring Org.:
USDOE
OSTI Identifier:
918898
Patent Number(s):
7289207
Application Number:
10/842,750
Assignee:
Los Alamos National Security, LLC (Los Alamos, NM)
Patent Classifications (CPCs):
B - PERFORMING OPERATIONS B82 - NANOTECHNOLOGY B82Y - SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES
G - PHYSICS G01 - MEASURING G01N - INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
DOE Contract Number:  
W-7405-ENG-36
Resource Type:
Patent
Country of Publication:
United States
Language:
English
Subject:
47 OTHER INSTRUMENTATION

Citation Formats

Grace, Karen M, Sweet, Martin R, Goeller, Roy M, Morrison, Leland Jean, Grace, Wynne Kevin, and Kolar, Jerome D. Integrated optical biosensor system (IOBS). United States: N. p., 2007. Web.
Grace, Karen M, Sweet, Martin R, Goeller, Roy M, Morrison, Leland Jean, Grace, Wynne Kevin, & Kolar, Jerome D. Integrated optical biosensor system (IOBS). United States.
Grace, Karen M, Sweet, Martin R, Goeller, Roy M, Morrison, Leland Jean, Grace, Wynne Kevin, and Kolar, Jerome D. Tue . "Integrated optical biosensor system (IOBS)". United States. https://www.osti.gov/servlets/purl/918898.
@article{osti_918898,
title = {Integrated optical biosensor system (IOBS)},
author = {Grace, Karen M and Sweet, Martin R and Goeller, Roy M and Morrison, Leland Jean and Grace, Wynne Kevin and Kolar, Jerome D},
abstractNote = {An optical biosensor has a first enclosure with a pathogen recognition surface, including a planar optical waveguide and grating located in the first enclosure. An aperture is in the first enclosure for insertion of sample to be investigated to a position in close proximity to the pathogen recognition surface. A laser in the first enclosure includes means for aligning and means for modulating the laser, the laser having its light output directed toward said grating. Detection means are located in the first enclosure and in optical communication with the pathogen recognition surface for detecting pathogens after interrogation by the laser light and outputting the detection. Electronic means is located in the first enclosure and receives the detection for processing the detection and outputting information on the detection, and an electrical power supply is located in the first enclosure for supplying power to the laser, the detection means and the electronic means.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {2007},
month = {10}
}

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Works referenced in this record:

Optical Biosensor Based on Fluorescence Resonance Energy Transfer:  Ultrasensitive and Specific Detection of Protein Toxins
journal, November 1998


Novel integrated optical sensor for DNA arrays detection
conference, October 2000


Reagentless optical biosensor
conference, March 2004

  • Grace, Karen M.; Goeller, Roy M.; Grace, W. K.
  • Optical Technologies for Industrial, Environmental, and Biological Sensing, SPIE Proceedings
  • https://doi.org/10.1117/12.516372