Autofluorescence detection and imaging of bladder cancer realized through a cystoscope

Demos, Stavros G; deVere White, Ralph W

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Title: Autofluorescence detection and imaging of bladder cancer realized through a cystoscope

Abstract

Near infrared imaging using elastic light scattering and tissue autofluorescence and utilizing interior examination techniques and equipment are explored for medical applications. The approach involves imaging using cross-polarized elastic light scattering and/or tissue autofluorescence in the Near Infra-Red (NIR) coupled with image processing and inter-image operations to differentiate human tissue components.

Inventors:

Demos, Stavros G ^[1]; deVere White, Ralph W ^[2]

Livermore, CA
Sacramento, CA

Issue Date:: Tue Aug 14 00:00:00 EDT 2007

Research Org.:: Lawrence Livermore National Laboratory (LLNL), Livermore, CA (United States)

Sponsoring Org.:: USDOE

OSTI Identifier:: 913440

Patent Number(s):: 7257437

Application Number:: 10/400,024

Assignee:: The Regents of the University of California (Oakland, CA)

Patent Classifications (CPCs):: A - HUMAN NECESSITIES A61 - MEDICAL OR VETERINARY SCIENCE A61B - DIAGNOSIS

G - PHYSICS G01 - MEASURING G01N - INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES

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A - HUMAN NECESSITIES A61 - MEDICAL OR VETERINARY SCIENCE A61B - DIAGNOSIS
A61B1/00186 - {with imaging filters}
A61B1/043 - {for fluorescence imaging}
A61B1/063 - {for monochromatic illumination}
A61B1/0638 - {providing two or more wavelengths}
A61B1/0646 - {with illumination filters}
A61B1/0669 - {at proximal end of an endoscope}
A61B1/307 - for the urinary organs, e.g. urethroscopes, cystoscopes
A61B1/313 - for introducing through surgical openings, e.g. laparoscopes
A61B5/0071 - {by measuring fluorescence emission}
A61B5/0075 - {by spectroscopy, i.e. measuring spectra, e.g. Raman spectroscopy, infrared absorption spectroscopy
A61B5/0086 - {using infra-red radiation}

G - PHYSICS G01 - MEASURING G01N - INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
G01N21/49 - within a body or fluid
G01N21/6445 - {Measuring fluorescence polarisation}

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DOE Contract Number:: W-7405-ENG-48

Resource Type:: Patent

Country of Publication:: United States

Language:: English

Subject:: 60 APPLIED LIFE SCIENCES

Citation Formats


                    Demos, Stavros G, and deVere White, Ralph W. Autofluorescence detection and imaging of bladder cancer realized through a cystoscope.  United States: N. p., 2007. 
        Web.

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                    Demos, Stavros G, & deVere White, Ralph W. Autofluorescence detection and imaging of bladder cancer realized through a cystoscope.  United States.

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                    Demos, Stavros G, and deVere White, Ralph W. Tue .  
        "Autofluorescence detection and imaging of bladder cancer realized through a cystoscope".  United States.  https://www.osti.gov/servlets/purl/913440.

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@article{osti_913440,

  title        = {Autofluorescence detection and imaging of bladder cancer realized through a cystoscope},

  author       = {Demos, Stavros G and deVere White, Ralph W},

  abstractNote = {Near infrared imaging using elastic light scattering and tissue autofluorescence and utilizing interior examination techniques and equipment are explored for medical applications. The approach involves imaging using cross-polarized elastic light scattering and/or tissue autofluorescence in the Near Infra-Red (NIR) coupled with image processing and inter-image operations to differentiate human tissue components.},

  doi          = {},

  journal      = {},
number       = ,

  volume       = ,

  place        = {United States},

  year         = {Tue Aug 14 00:00:00 EDT 2007},

  month        = {Tue Aug 14 00:00:00 EDT 2007}

}

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Works referenced in this record:

Tissue imaging for cancer detection using NIR autofluorescence
conference, May 2002

Demos, Stavros G.; Staggs, Michael C.; Gandour-Edwards, Regina
Proc. SPIE, Vol. 4613
https://doi.org/10.1117/12.465260

Autofluorescence characteristics of immortalized and carcinogen-transformed human bronchial epithelial cells
journal, January 2001

Pitts, Jonathan D.; Sloboda, Roger D.; Dragnev, Konstantin H.
Journal of Biomedical Optics, Vol. 6, Issue 1, p. 31-41
https://doi.org/10.1117/1.1333057

Laser induced fluorescence spectroscopy from native cancerous and normal tissue
journal, December 1984

Alfano, R.; Tata, D.; Cordero, J.
IEEE Journal of Quantum Electronics, Vol. 20, Issue 12, p. 1507-1511
https://doi.org/10.1109/JQE.1984.1072322

<title>Subsurface imaging using the spectral polarization difference technique and NIR illumination</title>
conference, July 1999

Demos, Stavros G.; Radousky, Harry B.; Alfano, Robert R.
Proc. SPIE, Vol. 3597
https://doi.org/10.1117/12.356824

Aberrant porphyrin metabolism in hepatocellular carcinoma
journal, April 1984

Udagawa, Misako; Horie, Yutaka; Hirayama, Chisato
Biochemical Medicine, Vol. 31, Issue 2, p. 131-139
https://doi.org/10.1016/0006-2944(84)90018-8

Spectroscopic Diagnosis Of Colonic Dysplasia
journal, June 1991

Richards-Kortum, R.; Rava, R. P.; Petras, R. E.
Photochemistry and Photobiology, Vol. 53, Issue 6, p. 777-786
https://doi.org/10.1111/j.1751-1097.1991.tb09892.x

Ultraviolet laser-induced fluorescence of colonic tissue: Basic biology and diagnostic potential
journal, January 1992

Schomacker, Kevin T.; Frisoli, Joan K.; Compton, Carolyn C.
Lasers in Surgery and Medicine, Vol. 12, Issue 1
https://doi.org/10.1002/lsm.1900120111

Destruction of erythroleukaemic cells by photoactivation of endogenous porphyrins
journal, November 1987

Malik, Z.; Lugaci, H.
British Journal of Cancer, Vol. 56, Issue 5
https://doi.org/10.1038/bjc.1987.246

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Similar Records

Title: Autofluorescence detection and imaging of bladder cancer realized through a cystoscope

Abstract

Citation Formats

Tissue imaging for cancer detection using NIR autofluorescence conference, May 2002

Autofluorescence characteristics of immortalized and carcinogen-transformed human bronchial epithelial cells journal, January 2001

Laser induced fluorescence spectroscopy from native cancerous and normal tissue journal, December 1984

<title>Subsurface imaging using the spectral polarization difference technique and NIR illumination</title> conference, July 1999

Aberrant porphyrin metabolism in hepatocellular carcinoma journal, April 1984

Spectroscopic Diagnosis Of Colonic Dysplasia journal, June 1991

Ultraviolet laser-induced fluorescence of colonic tissue: Basic biology and diagnostic potential journal, January 1992

Destruction of erythroleukaemic cells by photoactivation of endogenous porphyrins journal, November 1987

Tissue imaging for cancer detection using NIR autofluorescence
conference, May 2002

Autofluorescence characteristics of immortalized and carcinogen-transformed human bronchial epithelial cells
journal, January 2001

Laser induced fluorescence spectroscopy from native cancerous and normal tissue
journal, December 1984

<title>Subsurface imaging using the spectral polarization difference technique and NIR illumination</title>
conference, July 1999

Aberrant porphyrin metabolism in hepatocellular carcinoma
journal, April 1984

Spectroscopic Diagnosis Of Colonic Dysplasia
journal, June 1991

Ultraviolet laser-induced fluorescence of colonic tissue: Basic biology and diagnostic potential
journal, January 1992

Destruction of erythroleukaemic cells by photoactivation of endogenous porphyrins
journal, November 1987