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Title: Bioluminescent bioreporter integrated circuit devices and methods for detecting ammonia

Abstract

Monolithic bioelectronic devices for the detection of ammonia includes a microorganism that metabolizes ammonia and which harbors a lux gene fused with a heterologous promoter gene stably incorporated into the chromosome of the microorganism and an Optical Application Specific Integrated Circuit (OASIC). The microorganism is generally a bacterium.

Inventors:
 [1];  [1];  [2];  [3];  [1]
  1. Knoxville, TN
  2. Blaine, TN
  3. West Lafayette, IN
Issue Date:
Research Org.:
Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States)
Sponsoring Org.:
USDOE
OSTI Identifier:
908983
Patent Number(s):
7208286
Application Number:
11/152,139
Assignee:
UT-Battelle LLC (Oakridge, TN)
Patent Classifications (CPCs):
A - HUMAN NECESSITIES A61 - MEDICAL OR VETERINARY SCIENCE A61B - DIAGNOSIS
C - CHEMISTRY C12 - BIOCHEMISTRY C12Q - MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS
DOE Contract Number:  
FG05-94ER61870
Resource Type:
Patent
Country of Publication:
United States
Language:
English
Subject:
47 OTHER INSTRUMENTATION

Citation Formats

Simpson, Michael L, Paulus, Michael J, Sayler, Gary S, Applegate, Bruce M, and Ripp, Steven A. Bioluminescent bioreporter integrated circuit devices and methods for detecting ammonia. United States: N. p., 2007. Web.
Simpson, Michael L, Paulus, Michael J, Sayler, Gary S, Applegate, Bruce M, & Ripp, Steven A. Bioluminescent bioreporter integrated circuit devices and methods for detecting ammonia. United States.
Simpson, Michael L, Paulus, Michael J, Sayler, Gary S, Applegate, Bruce M, and Ripp, Steven A. Tue . "Bioluminescent bioreporter integrated circuit devices and methods for detecting ammonia". United States. https://www.osti.gov/servlets/purl/908983.
@article{osti_908983,
title = {Bioluminescent bioreporter integrated circuit devices and methods for detecting ammonia},
author = {Simpson, Michael L and Paulus, Michael J and Sayler, Gary S and Applegate, Bruce M and Ripp, Steven A},
abstractNote = {Monolithic bioelectronic devices for the detection of ammonia includes a microorganism that metabolizes ammonia and which harbors a lux gene fused with a heterologous promoter gene stably incorporated into the chromosome of the microorganism and an Optical Application Specific Integrated Circuit (OASIC). The microorganism is generally a bacterium.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {2007},
month = {4}
}

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