Continuous flow dielectrophoretic particle concentrator

Cummings, Eric B

Title: Continuous flow dielectrophoretic particle concentrator

Abstract

A continuous-flow filter/concentrator for separating and/or concentrating particles in a fluid is disclosed. The filter is a three-port device an inlet port, an filter port and a concentrate port. The filter separates particles into two streams by the ratio of their dielectrophoretic mobility to their electrokinetic, advective, or diffusive mobility if the dominant transport mechanism is electrokinesis, advection, or diffusion, respectively.Also disclosed is a device for separating and/or concentrating particles by dielectrophoretic trapping of the particles.

Inventors:

Cummings, Eric B ^[1]

Livermore, CA

Issue Date:: 2007-04-17

Research Org.:: Sandia National Lab. (SNL-CA), Livermore, CA (United States)

Sponsoring Org.:: USDOE

OSTI Identifier:: 908977

Patent Number(s):: 7204923

Application Number:: 10/176,322

Assignee:: Sandia National Laboratories (Livermore, CA)

Patent Classifications (CPCs):: B - PERFORMING OPERATIONS B03 - SEPARATION OF SOLID MATERIALS USING LIQUIDS OR USING PNEUMATIC TABLES OR JIGS B03C - MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS

G - PHYSICS G01 - MEASURING G01N - INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES

Show more

B - PERFORMING OPERATIONS B03 - SEPARATION OF SOLID MATERIALS USING LIQUIDS OR USING PNEUMATIC TABLES OR JIGS B03C - MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS
B03C5/005 - {Dielectrophoresis, i.e. dielectric particles migrating towards the region of highest field strength
B03C5/026 - {using open-gradient differential dielectric separation, i.e. using electrodes of special shapes for non-uniform field creation, e.g. Fluid Integrated Circuit [FIC]}

G - PHYSICS G01 - MEASURING G01N - INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
G01N15/0266 - {with electrical classification}

Show less

DOE Contract Number:: AC04-94AL85000

Resource Type:: Patent

Country of Publication:: United States

Language:: English

Subject:: 47 OTHER INSTRUMENTATION

Citation Formats


                    Cummings, Eric B. Continuous flow dielectrophoretic particle concentrator.  United States: N. p., 2007. 
        Web.

Copy to clipboard


                    Cummings, Eric B. Continuous flow dielectrophoretic particle concentrator.  United States.

Copy to clipboard


                    Cummings, Eric B. Tue .  
        "Continuous flow dielectrophoretic particle concentrator".  United States.  https://www.osti.gov/servlets/purl/908977.

Copy to clipboard


                    
@article{osti_908977,

  title        = {Continuous flow dielectrophoretic particle concentrator},

  author       = {Cummings, Eric B},

  abstractNote = {A continuous-flow filter/concentrator for separating and/or concentrating particles in a fluid is disclosed. The filter is a three-port device an inlet port, an filter port and a concentrate port. The filter separates particles into two streams by the ratio of their dielectrophoretic mobility to their electrokinetic, advective, or diffusive mobility if the dominant transport mechanism is electrokinesis, advection, or diffusion, respectively.Also disclosed is a device for separating and/or concentrating particles by dielectrophoretic trapping of the particles.},

  doi          = {},

  journal      = {},
number       = ,

  volume       = ,

  place        = {United States},

  year         = {2007},

  month        = {4}

}

Copy to clipboard

Patent:

Save / Share:

Export Metadata

Save to My Library

Works referenced in this record:

Dielectrophoretic trapping without embedded electrodes
conference, August 2000

Cummings, Eric B.; Singh, Anup K.
Micromachining and Microfabrication, SPIE Proceedings
https://doi.org/10.1117/12.395653

Similar Records in DOE Patents and OSTI.GOV collections:

Dielectrophoretic concentration of particles under electrokinetic flow

Patent Miles, Robin R.; Bettencourt, Kerry A.; Fuller, Christopher K.

The use of dielectrophoresis to collect particles under the conditions of electrokinetically-driven flow. Dielectrophortic concentration of particles under electrokinetic flow is accomplished by interdigitated electrodes patterned on an inner surface of a microfluid channel, a DC voltage is applied across the ends to the channel, and an AC voltage is applied across the electrodes, and particles swept down the channel electrokinetically are trapped within the field established by the electrodes. The particles can be released when the voltage to the electrodes is released.
Full Text Available
Methods and devices for high-throughput dielectrophoretic concentration

Patent Simmons, Blake A [San Francisco, CA]; Cummings, Eric B [Livermore, CA]; Fiechtner, Gregory J [Germantown, MD]; ...

Disclosed herein are methods and devices for assaying and concentrating analytes in a fluid sample using dielectrophoresis. As disclosed, the methods and devices utilize substrates having a plurality of pores through which analytes can be selectively prevented from passing, or inhibited, on application of an appropriate electric field waveform. The pores of the substrate produce nonuniform electric field having local extrema located near the pores. These nonuniform fields drive dielectrophoresis, which produces the inhibition. Arrangements of electrodes and porous substrates support continuous, bulk, multi-dimensional, and staged selective concentration.
Full Text Available
Movement of particles using sequentially activated dielectrophoretic particle trapping

Patent Miles, Robin R.

Manipulation of DNA and cells/spores using dielectrophoretic (DEP) forces to perform sample preparation protocols for polymerized chain reaction (PCR) based assays for various applications. This is accomplished by movement of particles using sequentially activated dielectrophoretic particle trapping. DEP forces induce a dipole in particles, and these particles can be trapped in non-uniform fields. The particles can be trapped in the high field strength region of one set of electrodes. By switching off this field and switching on an adjacent electrodes, particles can be moved down a channel with little or no flow.
Full Text Available
Hydrodynamic enhanced dielectrophoretic particle trapping

Patent Miles, Robin R.

Hydrodynamic enhanced dielectrophoretic particle trapping carried out by introducing a side stream into the main stream to squeeze the fluid containing particles close to the electrodes producing the dielelectrophoretic forces. The region of most effective or the strongest forces in the manipulating fields of the electrodes producing the dielectrophoretic forces is close to the electrodes, within 100 .mu.m from the electrodes. The particle trapping arrangement uses a series of electrodes with an AC field placed between pairs of electrodes, which causes trapping of particles along the edges of the electrodes. By forcing an incoming flow stream containing cells and DNA,more » « less
Full Text Available
Acoustic concentration of particles in fluid flow

Patent Ward, Michael W.; Kaduchak, Gregory

Disclosed herein is a acoustic concentration of particles in a fluid flow that includes a substantially acoustically transparent membrane and a vibration generator that define a fluid flow path therebetween. The fluid flow path is in fluid communication with a fluid source and a fluid outlet and the vibration generator is disposed adjacent the fluid flow path and is capable of producing an acoustic field in the fluid flow path. The acoustic field produces at least one pressure minima in the fluid flow path at a predetermined location within the fluid flow path and forces predetermined particles in the fluidmore » « less
Full Text Available

Similar Records

Title: Continuous flow dielectrophoretic particle concentrator

Abstract

Citation Formats

Dielectrophoretic trapping without embedded electrodes conference, August 2000

Dielectrophoretic trapping without embedded electrodes
conference, August 2000