High pressure capillary micro-fluidic valve device and a method of fabricating same
Abstract
A freeze-thaw valve and a method of micro-machining the freeze-thaw valve is provided and includes a valve housing, wherein the valve housing defines a housing cavity and includes a housing inlet, a housing vent, a capillary tubing inlet and a capillary tubing outlet. A valve body is provided, at least a portion of which is lithographically constructed, wherein the valve body includes a refrigerant inlet, a refrigerant outlet and an expansion chamber. The expansion chamber is disposed to communicate the refrigerant inlet with the refrigerant outlet and includes a restriction region having a flow restriction. Additionally, the valve body is disposed within the housing cavity to form an insulating channel between the valve housing and the valve body.
- Inventors:
-
- Fremont, CA
- Berkely, CA
- Milbury, MA
- Issue Date:
- Research Org.:
- Waters Investments Ltd. (New Castle, DE)
- Sponsoring Org.:
- USDOE
- OSTI Identifier:
- 908976
- Patent Number(s):
- 7204264
- Assignee:
- Waters Investments Ltd. (New Castle, DE)
- Patent Classifications (CPCs):
-
F - MECHANICAL ENGINEERING F16 - ENGINEERING ELEMENTS AND UNITS F16K - VALVES
Y - NEW / CROSS SECTIONAL TECHNOLOGIES Y10 - TECHNICAL SUBJECTS COVERED BY FORMER USPC Y10T - TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- DOE Contract Number:
- AC04-94AL85000
- Resource Type:
- Patent
- Country of Publication:
- United States
- Language:
- English
- Subject:
- 42 ENGINEERING
Citation Formats
Crocker, Robert W, Caton, Pamela F, and Gerhardt, Geoff C. High pressure capillary micro-fluidic valve device and a method of fabricating same. United States: N. p., 2007.
Web.
Crocker, Robert W, Caton, Pamela F, & Gerhardt, Geoff C. High pressure capillary micro-fluidic valve device and a method of fabricating same. United States.
Crocker, Robert W, Caton, Pamela F, and Gerhardt, Geoff C. Tue .
"High pressure capillary micro-fluidic valve device and a method of fabricating same". United States. https://www.osti.gov/servlets/purl/908976.
@article{osti_908976,
title = {High pressure capillary micro-fluidic valve device and a method of fabricating same},
author = {Crocker, Robert W and Caton, Pamela F and Gerhardt, Geoff C},
abstractNote = {A freeze-thaw valve and a method of micro-machining the freeze-thaw valve is provided and includes a valve housing, wherein the valve housing defines a housing cavity and includes a housing inlet, a housing vent, a capillary tubing inlet and a capillary tubing outlet. A valve body is provided, at least a portion of which is lithographically constructed, wherein the valve body includes a refrigerant inlet, a refrigerant outlet and an expansion chamber. The expansion chamber is disposed to communicate the refrigerant inlet with the refrigerant outlet and includes a restriction region having a flow restriction. Additionally, the valve body is disposed within the housing cavity to form an insulating channel between the valve housing and the valve body.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {2007},
month = {4}
}
Works referenced in this record:
Ultrahigh-Pressure Reversed-Phase Liquid Chromatography in Packed Capillary Columns
journal, March 1997
- MacNair, John E.; Lewis, Kenneth C.; Jorgenson, James W.
- Analytical Chemistry, Vol. 69, Issue 6
Ultrahigh-Pressure Reversed-Phase Capillary Liquid Chromatography: Isocratic and Gradient Elution Using Columns Packed with 1.0-μm Particles
journal, February 1999
- MacNair, John E.; Patel, Kamlesh D.; Jorgenson, James W.
- Analytical Chemistry, Vol. 71, Issue 3
Freeze-thaw flow management: a novel concept for high-performance liquid chromatography, capillary electrophoresis, electrochromatography and associated techniques
journal, April 1995
- Bevan, C. D.; Mutton, I. M.
- Journal of Chromatography A, Vol. 697, Issue 1-2
The Stableflow Pump−a low‐noise and drift‐free pump for high performance liquid chromatography
journal, June 1991
- LeBlanc, Jacques C.
- Review of Scientific Instruments, Vol. 62, Issue 6
Automated and Integrated System for High-Throughput DNA Genotyping Directly from Blood
journal, March 1999
- Zhang, Nanyan; Tan, Hongdong; Yeung, Edward S.
- Analytical Chemistry, Vol. 71, Issue 6