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Title: High pressure capillary micro-fluidic valve device and a method of fabricating same

Abstract

A freeze-thaw valve and a method of micro-machining the freeze-thaw valve is provided and includes a valve housing, wherein the valve housing defines a housing cavity and includes a housing inlet, a housing vent, a capillary tubing inlet and a capillary tubing outlet. A valve body is provided, at least a portion of which is lithographically constructed, wherein the valve body includes a refrigerant inlet, a refrigerant outlet and an expansion chamber. The expansion chamber is disposed to communicate the refrigerant inlet with the refrigerant outlet and includes a restriction region having a flow restriction. Additionally, the valve body is disposed within the housing cavity to form an insulating channel between the valve housing and the valve body.

Inventors:
 [1];  [2];  [3]
  1. Fremont, CA
  2. Berkely, CA
  3. Milbury, MA
Issue Date:
Research Org.:
Waters Investments Ltd. (New Castle, DE)
Sponsoring Org.:
USDOE
OSTI Identifier:
908976
Patent Number(s):
7204264
Assignee:
Waters Investments Ltd. (New Castle, DE)
Patent Classifications (CPCs):
F - MECHANICAL ENGINEERING F16 - ENGINEERING ELEMENTS AND UNITS F16K - VALVES
Y - NEW / CROSS SECTIONAL TECHNOLOGIES Y10 - TECHNICAL SUBJECTS COVERED BY FORMER USPC Y10T - TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
DOE Contract Number:  
AC04-94AL85000
Resource Type:
Patent
Country of Publication:
United States
Language:
English
Subject:
42 ENGINEERING

Citation Formats

Crocker, Robert W, Caton, Pamela F, and Gerhardt, Geoff C. High pressure capillary micro-fluidic valve device and a method of fabricating same. United States: N. p., 2007. Web.
Crocker, Robert W, Caton, Pamela F, & Gerhardt, Geoff C. High pressure capillary micro-fluidic valve device and a method of fabricating same. United States.
Crocker, Robert W, Caton, Pamela F, and Gerhardt, Geoff C. Tue . "High pressure capillary micro-fluidic valve device and a method of fabricating same". United States. https://www.osti.gov/servlets/purl/908976.
@article{osti_908976,
title = {High pressure capillary micro-fluidic valve device and a method of fabricating same},
author = {Crocker, Robert W and Caton, Pamela F and Gerhardt, Geoff C},
abstractNote = {A freeze-thaw valve and a method of micro-machining the freeze-thaw valve is provided and includes a valve housing, wherein the valve housing defines a housing cavity and includes a housing inlet, a housing vent, a capillary tubing inlet and a capillary tubing outlet. A valve body is provided, at least a portion of which is lithographically constructed, wherein the valve body includes a refrigerant inlet, a refrigerant outlet and an expansion chamber. The expansion chamber is disposed to communicate the refrigerant inlet with the refrigerant outlet and includes a restriction region having a flow restriction. Additionally, the valve body is disposed within the housing cavity to form an insulating channel between the valve housing and the valve body.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {2007},
month = {4}
}

Works referenced in this record:

Ultrahigh-Pressure Reversed-Phase Liquid Chromatography in Packed Capillary Columns
journal, March 1997


Ultrahigh-Pressure Reversed-Phase Capillary Liquid Chromatography:  Isocratic and Gradient Elution Using Columns Packed with 1.0-μm Particles
journal, February 1999


The Stableflow Pump−a low‐noise and drift‐free pump for high performance liquid chromatography
journal, June 1991


Automated and Integrated System for High-Throughput DNA Genotyping Directly from Blood
journal, March 1999