Method and apparatus for controlling cross contamination of microfluid channels

Rehm, Jason E; Paul, Phillip H; Arnold, Don W

Title: Method and apparatus for controlling cross contamination of microfluid channels

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Abstract

A method for controlling fluid flow at junctions in microchannel systems. Control of fluid flow is accomplished generally by providing increased resistance to electric-field and pressure-driven flow in the form of regions of reduced effective cross-sectional area within the microchannels and proximate a channel junction. By controlling these flows in the region of a microchannel junction it is possible to eliminate sample dispersion and cross contamination and inject well-defined volumes of fluid from one channel to another.

Inventors:

Hasselbrink, Jr., Ernest F. ^[1]; Rehm, Jason E ^[2]; Paul, Phillip H ^[3]; Arnold, Don W ^[3]

(Walnut Creek, CA)
Alameda, CA
Livermore, CA

Issue Date:: 2006-02-07

Research Org.:: Sandia National Lab. (SNL-CA), Livermore, CA (United States)

Sponsoring Org.:: USDOE

OSTI Identifier:: 908601

Patent Number(s):: 6994826

Application Number:: 09/669,862

Assignee:: Sandia National Laboratories (Livermore, CA)

Patent Classifications (CPCs):: B - PERFORMING OPERATIONS B01 - PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL B01L - CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE

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B - PERFORMING OPERATIONS B01 - PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL B01L - CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
B01L3/502746 - {characterised by the means for controlling flow resistance, e.g. flow controllers, baffles
B01L2200/0605 - Metering of fluids
B01L2400/0421 - electrophoretic flow
B01L2400/0487 - fluid pressure, pneumatics
B01L2400/0418 - electro-osmotic flow [EOF]
B01L2300/0861 - Configuration of multiple channels and/or chambers in a single devices
B01L2400/086 - using baffles or other fixed flow obstructions

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DOE Contract Number:: AC04-94AL85000

Resource Type:: Patent

Country of Publication:: United States

Language:: English

Subject:: 42 ENGINEERING

Citation Formats


                    Hasselbrink, Jr., Ernest F., Rehm, Jason E, Paul, Phillip H, and Arnold, Don W. Method and apparatus for controlling cross contamination of microfluid channels.  United States: N. p., 2006. 
        Web.

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                    Hasselbrink, Jr., Ernest F., Rehm, Jason E, Paul, Phillip H, & Arnold, Don W. Method and apparatus for controlling cross contamination of microfluid channels.  United States.

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                    Hasselbrink, Jr., Ernest F., Rehm, Jason E, Paul, Phillip H, and Arnold, Don W. Tue .  
        "Method and apparatus for controlling cross contamination of microfluid channels".  United States.  https://www.osti.gov/servlets/purl/908601.

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@article{osti_908601,

  title        = {Method and apparatus for controlling cross contamination of microfluid channels},

  author       = {Hasselbrink, Jr., Ernest F. and Rehm, Jason E and Paul, Phillip H and Arnold, Don W},

  abstractNote = {A method for controlling fluid flow at junctions in microchannel systems. Control of fluid flow is accomplished generally by providing increased resistance to electric-field and pressure-driven flow in the form of regions of reduced effective cross-sectional area within the microchannels and proximate a channel junction. By controlling these flows in the region of a microchannel junction it is possible to eliminate sample dispersion and cross contamination and inject well-defined volumes of fluid from one channel to another.},

  doi          = {},

  journal      = {},
number       = ,

  volume       = ,

  place        = {United States},

  year         = {2006},

  month        = {2}

}

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