Low power integrated pumping and valving arrays for microfluidic systems
Abstract
Low power integrated pumping and valving arrays which provide a revolutionary approach for performing pumping and valving approach for performing pumping and valving operations in microfabricated fluidic systems for applications such as medical diagnostic microchips. Traditional methods rely on external, large pressure sources that defeat the advantages of miniaturization. Previously demonstrated microfabrication devices are power and voltage intensive, only function at sufficient pressure to be broadly applicable. This approach integrates a lower power, high-pressure source with a polymer, ceramic, or metal plug enclosed within a microchannel, analogous to a microsyringe. When the pressure source is activated, the polymer plug slides within the microchannel, pumping the fluid on the opposite side of the plug without allowing fluid to leak around the plug. The plugs also can serve as microvalves.
- Inventors:
-
- Pleasanton, CA
- Livermore, CA
- Tracy, CA
- Davis, CA
- Issue Date:
- Research Org.:
- Lawrence Livermore National Laboratory (LLNL), Livermore, CA (United States)
- Sponsoring Org.:
- USDOE
- OSTI Identifier:
- 908529
- Patent Number(s):
- 7025323
- Application Number:
- 09/957,894
- Assignee:
- The Regents of the University of California (Oakland, CA)
- Patent Classifications (CPCs):
-
F - MECHANICAL ENGINEERING F15 - FLUID-PRESSURE ACTUATORS F15C - FLUID-CIRCUIT ELEMENTS PREDOMINANTLY USED FOR COMPUTING OR CONTROL PURPOSES
F - MECHANICAL ENGINEERING F16 - ENGINEERING ELEMENTS AND UNITS F16K - VALVES
- DOE Contract Number:
- W-7405-ENG-48
- Resource Type:
- Patent
- Country of Publication:
- United States
- Language:
- English
- Subject:
- 42 ENGINEERING
Citation Formats
Krulevitch, Peter A, Benett, William J, Rose, Klint A, Hamilton, Julie, and Maghribi, Mariam. Low power integrated pumping and valving arrays for microfluidic systems. United States: N. p., 2006.
Web.
Krulevitch, Peter A, Benett, William J, Rose, Klint A, Hamilton, Julie, & Maghribi, Mariam. Low power integrated pumping and valving arrays for microfluidic systems. United States.
Krulevitch, Peter A, Benett, William J, Rose, Klint A, Hamilton, Julie, and Maghribi, Mariam. Tue .
"Low power integrated pumping and valving arrays for microfluidic systems". United States. https://www.osti.gov/servlets/purl/908529.
@article{osti_908529,
title = {Low power integrated pumping and valving arrays for microfluidic systems},
author = {Krulevitch, Peter A and Benett, William J and Rose, Klint A and Hamilton, Julie and Maghribi, Mariam},
abstractNote = {Low power integrated pumping and valving arrays which provide a revolutionary approach for performing pumping and valving approach for performing pumping and valving operations in microfabricated fluidic systems for applications such as medical diagnostic microchips. Traditional methods rely on external, large pressure sources that defeat the advantages of miniaturization. Previously demonstrated microfabrication devices are power and voltage intensive, only function at sufficient pressure to be broadly applicable. This approach integrates a lower power, high-pressure source with a polymer, ceramic, or metal plug enclosed within a microchannel, analogous to a microsyringe. When the pressure source is activated, the polymer plug slides within the microchannel, pumping the fluid on the opposite side of the plug without allowing fluid to leak around the plug. The plugs also can serve as microvalves.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {Tue Apr 11 00:00:00 EDT 2006},
month = {Tue Apr 11 00:00:00 EDT 2006}
}