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Title: Low power integrated pumping and valving arrays for microfluidic systems

Abstract

Low power integrated pumping and valving arrays which provide a revolutionary approach for performing pumping and valving approach for performing pumping and valving operations in microfabricated fluidic systems for applications such as medical diagnostic microchips. Traditional methods rely on external, large pressure sources that defeat the advantages of miniaturization. Previously demonstrated microfabrication devices are power and voltage intensive, only function at sufficient pressure to be broadly applicable. This approach integrates a lower power, high-pressure source with a polymer, ceramic, or metal plug enclosed within a microchannel, analogous to a microsyringe. When the pressure source is activated, the polymer plug slides within the microchannel, pumping the fluid on the opposite side of the plug without allowing fluid to leak around the plug. The plugs also can serve as microvalves.

Inventors:
 [1];  [2];  [2];  [3];  [4]
  1. Pleasanton, CA
  2. Livermore, CA
  3. Tracy, CA
  4. Davis, CA
Issue Date:
Research Org.:
Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States)
Sponsoring Org.:
USDOE
OSTI Identifier:
908529
Patent Number(s):
7025323
Application Number:
09/957,894
Assignee:
The Regents of the University of California (Oakland, CA)
Patent Classifications (CPCs):
F - MECHANICAL ENGINEERING F16 - ENGINEERING ELEMENTS AND UNITS F16K - VALVES
F - MECHANICAL ENGINEERING F15 - FLUID-PRESSURE ACTUATORS F15C - FLUID-CIRCUIT ELEMENTS PREDOMINANTLY USED FOR COMPUTING OR CONTROL PURPOSES
DOE Contract Number:  
W-7405-ENG-48
Resource Type:
Patent
Country of Publication:
United States
Language:
English
Subject:
42 ENGINEERING

Citation Formats

Krulevitch, Peter A, Benett, William J, Rose, Klint A, Hamilton, Julie, and Maghribi, Mariam. Low power integrated pumping and valving arrays for microfluidic systems. United States: N. p., 2006. Web.
Krulevitch, Peter A, Benett, William J, Rose, Klint A, Hamilton, Julie, & Maghribi, Mariam. Low power integrated pumping and valving arrays for microfluidic systems. United States.
Krulevitch, Peter A, Benett, William J, Rose, Klint A, Hamilton, Julie, and Maghribi, Mariam. Tue . "Low power integrated pumping and valving arrays for microfluidic systems". United States. https://www.osti.gov/servlets/purl/908529.
@article{osti_908529,
title = {Low power integrated pumping and valving arrays for microfluidic systems},
author = {Krulevitch, Peter A and Benett, William J and Rose, Klint A and Hamilton, Julie and Maghribi, Mariam},
abstractNote = {Low power integrated pumping and valving arrays which provide a revolutionary approach for performing pumping and valving approach for performing pumping and valving operations in microfabricated fluidic systems for applications such as medical diagnostic microchips. Traditional methods rely on external, large pressure sources that defeat the advantages of miniaturization. Previously demonstrated microfabrication devices are power and voltage intensive, only function at sufficient pressure to be broadly applicable. This approach integrates a lower power, high-pressure source with a polymer, ceramic, or metal plug enclosed within a microchannel, analogous to a microsyringe. When the pressure source is activated, the polymer plug slides within the microchannel, pumping the fluid on the opposite side of the plug without allowing fluid to leak around the plug. The plugs also can serve as microvalves.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {2006},
month = {4}
}