DOE Patents DOE Patents
DOE Patents title logo U.S. Department of Energy
Office of Scientific and Technical Information
Search DOE Patents

Title: Methanobactin: a copper binding compound having antibiotic and antioxidant activity isolated from methanotrophic bacteria

Abstract

A means and method for treating bacterial infection, providing antioxidant activity, and chelating copper using a copper binding compound produced by methanotrophic bacteria is described. The compound, known as methanobactin, is the first of a new class of antibiotics having gram-positive activity. Methanobactin has been sequenced, and its structural formula determined.

Inventors:
 [1];  [2];  [3];  [4];  [3];  [3]
+ Show Inventor Affiliations
  1. Ames, IA
  2. Harbor Beach, MI
  3. Lawrence, KS
  4. St. Paul, MN
Issue Date:
Research Org.:
Iowa State Univ., Ames, IA (United States)
Sponsoring Org.:
USDOE
OSTI Identifier:
907754
Patent Number(s):
7199099
Application Number:
10/741,831
Assignee:
The University of Kansas (Lawrence, KS); Iowa State University Research Foundation, Inc. (Ames, IA)
Patent Classifications (CPCs):
A - HUMAN NECESSITIES A61 - MEDICAL OR VETERINARY SCIENCE A61K - PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
C - CHEMISTRY C07 - ORGANIC CHEMISTRY C07K - PEPTIDES
Show more
DOE Contract Number:  
FG02-96ER20237
Resource Type:
Patent
Country of Publication:
United States
Language:
English
Subject:
59 BASIC BIOLOGICAL SCIENCES

Citation Formats

DiSpirito, Alan A, Zahn, James A, Graham, David W, Kim, Hyung J, Alterman, Michail, and Larive, Cynthia. Methanobactin: a copper binding compound having antibiotic and antioxidant activity isolated from methanotrophic bacteria. United States: N. p., 2007. Web.
Copy to clipboard
DiSpirito, Alan A, Zahn, James A, Graham, David W, Kim, Hyung J, Alterman, Michail, & Larive, Cynthia. Methanobactin: a copper binding compound having antibiotic and antioxidant activity isolated from methanotrophic bacteria. United States.
Copy to clipboard
DiSpirito, Alan A, Zahn, James A, Graham, David W, Kim, Hyung J, Alterman, Michail, and Larive, Cynthia. Tue . "Methanobactin: a copper binding compound having antibiotic and antioxidant activity isolated from methanotrophic bacteria". United States. https://www.osti.gov/servlets/purl/907754.
Copy to clipboard
@article{osti_907754,
title = {Methanobactin: a copper binding compound having antibiotic and antioxidant activity isolated from methanotrophic bacteria},
author = {DiSpirito, Alan A and Zahn, James A and Graham, David W and Kim, Hyung J and Alterman, Michail and Larive, Cynthia},
abstractNote = {A means and method for treating bacterial infection, providing antioxidant activity, and chelating copper using a copper binding compound produced by methanotrophic bacteria is described. The compound, known as methanobactin, is the first of a new class of antibiotics having gram-positive activity. Methanobactin has been sequenced, and its structural formula determined.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {2007},
month = {4}
}
Copy to clipboard
Patent:
View Patent
Save / Share:
Export Metadata
Save to My Library
You must Sign In or Create an Account in order to save documents to your library.

Works referenced in this record:

Expression of soluble methane monooxygenase genes
journal, November 2002

Tissue injury by reactive oxygen species and the protective effects of flavonoids
journal, May 1998

Particulate methane monooxygenase from Methylosinus trichosporium is a copper-containing enzyme
journal, July 2002

Isolation of Copper Biochelates fromMethylosinus trichosporium OB3b and Soluble Methane Monooxygenase Mutants
journal, March 1998

Oxidativer Stress, altersabhängige Zellschädigungen und antioxidative Mechanismen
journal, April 2002

    [ × clear filter / sort ]

    Similar Records in DOE Patents and OSTI.GOV collections: