Target molecules detection by waveguiding in a photonic silicon membrane

Letant, Sonia E; Van Buuren, Anthony; Terminello, Louis; Hart, Bradley R

Title: Target molecules detection by waveguiding in a photonic silicon membrane

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Abstract

Disclosed herein is a porous silicon filter capable of binding and detecting biological and chemical target molecules in liquid or gas samples. A photonic waveguiding silicon filter with chemical and/or biological anchors covalently attached to the pore walls bind target molecules. The system uses transmission curve engineering principles to allow measurements to be made in situ and in real time to detect the presence of various target molecules and calculate the concentration of bound target.

Inventors:

Letant, Sonia E ^[1]; Van Buuren, Anthony ^[1]; Terminello, Louis ^[2]; Hart, Bradley R ^[3]

Livermore, CA
Danville, CA
Brentwood, CA

Issue Date:: 2006-12-26

Research Org.:: Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States)

Sponsoring Org.:: USDOE

OSTI Identifier:: 904222

Patent Number(s):: 7155076

Application Number:: 10/833,573

Assignee:: The Regents of the University of California (Oakland, CA)

Patent Classifications (CPCs):: G - PHYSICS G01 - MEASURING G01N - INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES

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G - PHYSICS G01 - MEASURING G01N - INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
G01N33/553 - Metal or metal coated
G01N21/774 - {the reagent being on a grating or periodic structure}
G01N2021/7783 - {Transmission, loss}
G01N33/54373 - {involving physiochemical end-point determination, e.g. wave-guides, FETS, gratings}
G01N21/783 - {for analysing gases}

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DOE Contract Number:: W-7405-ENG-48

Resource Type:: Patent

Country of Publication:: United States

Language:: English

Subject:: 47 OTHER INSTRUMENTATION

Citation Formats


                    Letant, Sonia E, Van Buuren, Anthony, Terminello, Louis, and Hart, Bradley R. Target molecules detection by waveguiding in a photonic silicon membrane.  United States: N. p., 2006. 
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                    Letant, Sonia E, Van Buuren, Anthony, Terminello, Louis, & Hart, Bradley R. Target molecules detection by waveguiding in a photonic silicon membrane.  United States.

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                    Letant, Sonia E, Van Buuren, Anthony, Terminello, Louis, and Hart, Bradley R. Tue .  
        "Target molecules detection by waveguiding in a photonic silicon membrane".  United States.  https://www.osti.gov/servlets/purl/904222.

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@article{osti_904222,

  title        = {Target molecules detection by waveguiding in a photonic silicon membrane},

  author       = {Letant, Sonia E and Van Buuren, Anthony and Terminello, Louis and Hart, Bradley R},

  abstractNote = {Disclosed herein is a porous silicon filter capable of binding and detecting biological and chemical target molecules in liquid or gas samples. A photonic waveguiding silicon filter with chemical and/or biological anchors covalently attached to the pore walls bind target molecules. The system uses transmission curve engineering principles to allow measurements to be made in situ and in real time to detect the presence of various target molecules and calculate the concentration of bound target.},

  doi          = {},

  journal      = {},
number       = ,

  volume       = ,

  place        = {United States},

  year         = {2006},

  month        = {12}

}

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Target molecules detection by waveguiding in a photonic silicon membrane

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Disclosed herein is a photonic silicon filter capable of binding and detecting biological and chemical target molecules in liquid or gas samples. A photonic waveguiding silicon filter with chemical and/or biological anchors covalently attached to the pore walls selectively bind target molecules. The system uses transmission curve engineering principles to allow measurements to be made in situ and in real time to detect the presence of various target molecules and determine the concentration of bound target.
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