Systems For Column-Based Separations, Methods Of Forming Packed Columns, And Methods Of Purifying Sample Components.
Abstract
The invention encompasses systems for column-based separations, methods of packing and unpacking columns and methods of separating components of samples. In one aspect, the invention includes a method of packing and unpacking a column chamber, comprising: a) packing a matrix material within a column chamber to form a packed column; and b) after the packing, unpacking the matrix material from the column chamber without moving the column chamber. In another aspect, the invention includes a system for column-based separations, comprising: a) a fluid passageway, the fluid passageway comprising a column chamber and a flow path in fluid communication with the column chamber, the flow path being obstructed by a retaining material permeable to a carrier fluid and impermeable to a column matrix material suspended in the carrier fluid, the flow path extending through the column chamber and through the retaining material, the flow path being configured to form a packed column within the column chamber when a suspension of the fluid and the column matrix material is flowed along the flow path; and b) the fluid passageway extending through a valve intermediate the column chamber and the retaining material.
- Inventors:
-
- Richland, WA
- West Richland, WA
- Kennewick, WA
- Issue Date:
- Research Org.:
- Pacific Northwest National Laboratory (PNNL), Richland, WA (United States)
- OSTI Identifier:
- 880254
- Patent Number(s):
- 6780326
- Application Number:
- 10/703815
- Assignee:
- Battelle Memorial Institute (Richland, WA)
- Patent Classifications (CPCs):
-
B - PERFORMING OPERATIONS B01 - PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL B01D - SEPARATION
G - PHYSICS G01 - MEASURING G01N - INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- DOE Contract Number:
- AC06-76RL01830
- Resource Type:
- Patent
- Country of Publication:
- United States
- Language:
- English
Citation Formats
Egorov, Oleg B, O'Hara, Matthew J, Grate, Jay W, Chandler, Darrell P, Brockman, Fred J, and Bruckner-Lea, Cynthia J. Systems For Column-Based Separations, Methods Of Forming Packed Columns, And Methods Of Purifying Sample Components.. United States: N. p., 2004.
Web.
Egorov, Oleg B, O'Hara, Matthew J, Grate, Jay W, Chandler, Darrell P, Brockman, Fred J, & Bruckner-Lea, Cynthia J. Systems For Column-Based Separations, Methods Of Forming Packed Columns, And Methods Of Purifying Sample Components.. United States.
Egorov, Oleg B, O'Hara, Matthew J, Grate, Jay W, Chandler, Darrell P, Brockman, Fred J, and Bruckner-Lea, Cynthia J. Tue .
"Systems For Column-Based Separations, Methods Of Forming Packed Columns, And Methods Of Purifying Sample Components.". United States. https://www.osti.gov/servlets/purl/880254.
@article{osti_880254,
title = {Systems For Column-Based Separations, Methods Of Forming Packed Columns, And Methods Of Purifying Sample Components.},
author = {Egorov, Oleg B and O'Hara, Matthew J and Grate, Jay W and Chandler, Darrell P and Brockman, Fred J and Bruckner-Lea, Cynthia J},
abstractNote = {The invention encompasses systems for column-based separations, methods of packing and unpacking columns and methods of separating components of samples. In one aspect, the invention includes a method of packing and unpacking a column chamber, comprising: a) packing a matrix material within a column chamber to form a packed column; and b) after the packing, unpacking the matrix material from the column chamber without moving the column chamber. In another aspect, the invention includes a system for column-based separations, comprising: a) a fluid passageway, the fluid passageway comprising a column chamber and a flow path in fluid communication with the column chamber, the flow path being obstructed by a retaining material permeable to a carrier fluid and impermeable to a column matrix material suspended in the carrier fluid, the flow path extending through the column chamber and through the retaining material, the flow path being configured to form a packed column within the column chamber when a suspension of the fluid and the column matrix material is flowed along the flow path; and b) the fluid passageway extending through a valve intermediate the column chamber and the retaining material.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {Tue Aug 24 00:00:00 EDT 2004},
month = {Tue Aug 24 00:00:00 EDT 2004}
}