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Title: Method For Detecting Biological Agents

Abstract

A sensor is provided including a polymer capable of having an alterable measurable property from the group of luminescence and electrical conductivity, the polymer having an intermediate combination of a recognition element, a tethering element and a property-altering element bound thereto and capable of altering the measurable property, the intermediate combination adapted for subsequent separation from the polymer upon exposure to an agent having an affinity for binding to the recognition element whereupon the separation of the intermediate combination from the polymer results in a detectable change in the alterable measurable property, and, detecting said detectable change in the alterable measurable property.

Inventors:
 [1];  [2];  [1];  [2]
  1. Los Alamos, NM
  2. Santa Fe, NM
Issue Date:
Research Org.:
Los Alamos National Lab. (LANL), Los Alamos, NM (United States)
OSTI Identifier:
879994
Patent Number(s):
6979543
Application Number:
10/412568
Assignee:
The Regents of the University of California (Los Alamos, NM)
Patent Classifications (CPCs):
G - PHYSICS G01 - MEASURING G01N - INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
Y - NEW / CROSS SECTIONAL TECHNOLOGIES Y10 - TECHNICAL SUBJECTS COVERED BY FORMER USPC Y10S - TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
DOE Contract Number:  
W-7405-ENG-36
Resource Type:
Patent
Country of Publication:
United States
Language:
English

Citation Formats

Chen, Liaohai, McBranch, Duncan W, Wang, Hsing-Lin, and Whitten, David G. Method For Detecting Biological Agents. United States: N. p., 2005. Web.
Chen, Liaohai, McBranch, Duncan W, Wang, Hsing-Lin, & Whitten, David G. Method For Detecting Biological Agents. United States.
Chen, Liaohai, McBranch, Duncan W, Wang, Hsing-Lin, and Whitten, David G. Tue . "Method For Detecting Biological Agents". United States. https://www.osti.gov/servlets/purl/879994.
@article{osti_879994,
title = {Method For Detecting Biological Agents},
author = {Chen, Liaohai and McBranch, Duncan W and Wang, Hsing-Lin and Whitten, David G},
abstractNote = {A sensor is provided including a polymer capable of having an alterable measurable property from the group of luminescence and electrical conductivity, the polymer having an intermediate combination of a recognition element, a tethering element and a property-altering element bound thereto and capable of altering the measurable property, the intermediate combination adapted for subsequent separation from the polymer upon exposure to an agent having an affinity for binding to the recognition element whereupon the separation of the intermediate combination from the polymer results in a detectable change in the alterable measurable property, and, detecting said detectable change in the alterable measurable property.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {2005},
month = {12}
}

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Works referenced in this record:

Fluorescent Chemosensors Based on Energy Migration in Conjugated Polymers: The Molecular Wire Approach to Increased Sensitivity
journal, December 1995