Method And Apparatus For Examining A Tissue Using The Spectral Wing Emission Therefrom Induced By Visible To Infrared Photoexcitation.

Title: Method And Apparatus For Examining A Tissue Using The Spectral Wing Emission Therefrom Induced By Visible To Infrared Photoexcitation.

Full Record
Other Related Research

Abstract

Method and an apparatus for examining a tissue using the spectral wing emission therefrom induced by visible to infrared photoexcitation. In one aspect, the method is used to characterize the condition of a tissue sample and comprises the steps of (a) photoexciting the tissue sample with substantially monochromatic light having a wavelength of at least 600 nm; and (b) using the resultant far red and near infrared spectral wing emission (SW) emitted from the tissue sample to characterize the condition of the tissue sample. In one embodiment, the substantially monochromatic photoexciting light is a continuous beam of light, and the resultant steady-state far red and near infrared SW emission from the tissue sample is used to characterize the condition of the tissue sample. In another embodiment, the substantially monochromatic photoexciting light is a light pulse, and the resultant time-resolved far red and near infrared SW emission emitted from the tissue sample is used to characterize the condition of the tissue sample. In still another embodiment, the substantially monochromatic photoexciting light is a polarized light pulse, and the parallel and perpendicular components of the resultant polarized time-resolved SW emission emitted from the tissue sample are used to characterize the condition ofmore » the tissue sample.« less

Inventors:

Alfano, Robert R. ^[1]; Demos, Stavros G. ^[2]; Zhang, Gang ^[3]

(3777 Independence Ave., Bronx, NY 10463)
(3550 Pacific Ave., Apt. 304, Livermore, CA 94550)
(3 Rieder Rd., Edison, NJ 08817)

Issue Date:: 2003-12-16

Research Org.:: CITY UNIV OF NEW YORK RES FDN

OSTI Identifier:: 879642

Patent Number(s):: 6,665,556

Application Number:: 09/493939

Assignee:: Alfano, Robert R. (3777 Independence Ave., Bronx, NY 10463); Demos, Stavros G. (3550 Pacific Ave., Apt. 304, Livermore, CA 94550); Zhang, Gang (3 Rieder Rd., Edison, NJ 08817) CHO

DOE Contract Number:: FG02-98ER62560

Resource Type:: Patent

Country of Publication:: United States

Language:: English

Citation Formats


                    Alfano, Robert R., Demos, Stavros G., and Zhang, Gang. Method And Apparatus For Examining A Tissue Using The Spectral Wing Emission Therefrom Induced By Visible To Infrared Photoexcitation..  United States: N. p., 2003. 
        Web.

Copy to clipboard


                    Alfano, Robert R., Demos, Stavros G., & Zhang, Gang. Method And Apparatus For Examining A Tissue Using The Spectral Wing Emission Therefrom Induced By Visible To Infrared Photoexcitation..  United States.

Copy to clipboard


                    Alfano, Robert R., Demos, Stavros G., and Zhang, Gang. Tue .  
        "Method And Apparatus For Examining A Tissue Using The Spectral Wing Emission Therefrom Induced By Visible To Infrared Photoexcitation.".  United States.  https://www.osti.gov/servlets/purl/879642.

Copy to clipboard


                    
@article{osti_879642,

  title        = {Method And Apparatus For Examining A Tissue Using The Spectral Wing Emission Therefrom Induced By Visible To Infrared Photoexcitation.},

  author       = {Alfano, Robert R. and Demos, Stavros G. and Zhang, Gang},

  abstractNote = {Method and an apparatus for examining a tissue using the spectral wing emission therefrom induced by visible to infrared photoexcitation. In one aspect, the method is used to characterize the condition of a tissue sample and comprises the steps of (a) photoexciting the tissue sample with substantially monochromatic light having a wavelength of at least 600 nm; and (b) using the resultant far red and near infrared spectral wing emission (SW) emitted from the tissue sample to characterize the condition of the tissue sample. In one embodiment, the substantially monochromatic photoexciting light is a continuous beam of light, and the resultant steady-state far red and near infrared SW emission from the tissue sample is used to characterize the condition of the tissue sample. In another embodiment, the substantially monochromatic photoexciting light is a light pulse, and the resultant time-resolved far red and near infrared SW emission emitted from the tissue sample is used to characterize the condition of the tissue sample. In still another embodiment, the substantially monochromatic photoexciting light is a polarized light pulse, and the parallel and perpendicular components of the resultant polarized time-resolved SW emission emitted from the tissue sample are used to characterize the condition of the tissue sample.},

  doi          = {},

  journal      = {},
number       = ,

  volume       = ,

  place        = {United States},

  year         = {2003},

  month        = {12}

}

Copy to clipboard

Patent:

View Patent

Save / Share:

Export Metadata

Save to My Library

Similar records in DOE Patents and OSTI.GOV collections:

Interferometric apparatus and method for detection and characterization of particles using light scattered therefrom

Patent Johnston, Roger G. (Los Alamos, NM)

Interferometric apparatus and method for detection and characterization of particles using light scattered therefrom. Differential phase measurements on scattered light from particles are possible using the two-frequency Zeeman effect laser which emits two frequencies of radiation 250 kHz apart. Excellent discrimination and reproducibility for various pure pollen and bacterial samples in suspension have been observed with a single polarization element. Additionally, a 250 kHz beat frequency was recorded from an individual particle traversing the focused output from the laser in a flow cytometer.
Full Text Available
Apparatus and method for transient thermal infrared emission spectrometry

Patent McClelland, John F. (Ames, IA); Jones, Roger W. (Ames, IA)

A method and apparatus for enabling analysis of a solid material (16, 42) by applying energy from an energy source (20, 70) top a surface region of the solid material sufficient to cause transient heating in a thin surface layer portion of the solid material (16, 42) so as to enable transient thermal emission of infrared radiation from the thin surface layer portion, and by detecting with a spectrometer/detector (28, 58) substantially only the transient thermal emission of infrared radiation from the thin surface layer portion of the solid material. The detected transient thermal emission of infrared radiation is sufficientlymore »« less
Full Text Available
Method and apparatus for enhanced sequencing of complex molecules using surface-induced dissociation in conjunction with mass spectrometric analysis

Patent Laskin, Julia [Richland, WA]; Futrell, Jean H [Richland, WA]

The invention relates to a method and apparatus for enhanced sequencing of complex molecules using surface-induced dissociation (SID) in conjunction with mass spectrometric analysis. Results demonstrate formation of a wide distribution of structure-specific fragments having wide sequence coverage useful for sequencing and identifying the complex molecules.
Full Text Available
Method for digesting spent ion exchange resins and recovering actinides therefrom using microwave radiation

Patent Maxwell, III, Sherrod L. (Aiken, SC); Nichols, Sheldon T. (Augusta, GA)

The present invention relates to methods for digesting diphosphonic acid substituted cation exchange resins that have become loaded with actinides, rare earth metals, or heavy metals, in a way that allows for downstream chromatographic analysis of the adsorbed species without damage to or inadequate elution from the downstream chromatographic resins. The methods of the present invention involve contacting the loaded diphosphonic acid resin with concentrated oxidizing acid in a closed vessel, and irradiating this mixture with microwave radiation. This efficiently increases the temperature of the mixture to a level suitable for digestion of the resin without the use of dehydratingmore »« less
Full Text Available
Method And System For Examining Biological Materials Using Low Power Cw Excitation Raman Spectroscopy.

Patent Alfano, Robert R. (Bronx, NY); Wang, Wubao (Flushing, NY)

A method and system for examining biological materials using low-power cw excitation Raman spectroscopy. In accordance with the teachings of the invention, a low-power continuous wave (cw) pump laser beam and a low-power cw Stokes (or anti-Stokes) probe laser beam simultaneously illuminate a biological material and traverse the biological material in collinearity. The pump beam, whose frequency is varied, is used to induce Raman emission from the biological material. The intensity of the probe beam, whose frequency is kept constant, is monitored as it leaves the biological material. When the difference between the pump and probe excitation frequencies is equalmore »« less
Full Text Available

Similar Records