Uniform laser excitation and detection in capillary array electrophoresis system and method
Abstract
A capillary electrophoresis system comprises capillaries positioned in parallel to each other forming a plane. The capillaries are configured to allow samples to migrate. A light source is configured to illuminate the capillaries and the samples therein. This causes the samples to emit light. A lens is configured to receive the light emitted by the samples and positioned directly over a first group of the capillaries and obliquely over a second group of the capillaries. The light source is further configured to illuminate the second group of capillaries more than the first group of the capillaries such that amount of light received by the lens from the first group of capillaries is substantially identical to amount of light received from the second group of capillaries when an identical amount of the samples is migrating through the first and second group capillaries.
- Inventors:
- Issue Date:
- Research Org.:
- I. Reich Family Limited Partnership, New York, NY (United States)
- Sponsoring Org.:
- USDOE
- OSTI Identifier:
- 879618
- Patent Number(s):
- 6630063
- Application Number:
- 09/413,355
- Assignee:
- I. Reich Family Limited Partnership (New York, NY)
- Patent Classifications (CPCs):
-
G - PHYSICS G01 - MEASURING G01N - INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- DOE Contract Number:
- FG02-97ER82461
- Resource Type:
- Patent
- Resource Relation:
- Patent File Date: 1999 Oct 06
- Country of Publication:
- United States
- Language:
- English
Citation Formats
Li, Qingbo, Zhou, Songsan, and Liu, Changsheng. Uniform laser excitation and detection in capillary array electrophoresis system and method. United States: N. p., 2003.
Web.
Li, Qingbo, Zhou, Songsan, & Liu, Changsheng. Uniform laser excitation and detection in capillary array electrophoresis system and method. United States.
Li, Qingbo, Zhou, Songsan, and Liu, Changsheng. Tue .
"Uniform laser excitation and detection in capillary array electrophoresis system and method". United States. https://www.osti.gov/servlets/purl/879618.
@article{osti_879618,
title = {Uniform laser excitation and detection in capillary array electrophoresis system and method},
author = {Li, Qingbo and Zhou, Songsan and Liu, Changsheng},
abstractNote = {A capillary electrophoresis system comprises capillaries positioned in parallel to each other forming a plane. The capillaries are configured to allow samples to migrate. A light source is configured to illuminate the capillaries and the samples therein. This causes the samples to emit light. A lens is configured to receive the light emitted by the samples and positioned directly over a first group of the capillaries and obliquely over a second group of the capillaries. The light source is further configured to illuminate the second group of capillaries more than the first group of the capillaries such that amount of light received by the lens from the first group of capillaries is substantially identical to amount of light received from the second group of capillaries when an identical amount of the samples is migrating through the first and second group capillaries.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {Tue Oct 07 00:00:00 EDT 2003},
month = {Tue Oct 07 00:00:00 EDT 2003}
}