DOE Patents title logo U.S. Department of Energy
Office of Scientific and Technical Information

Title: Photosensitizer Conjugates For Pathogen Targeting

Abstract

Conjugate molecules which include photosensitizer compositions conjugated to non-antibody non-affinity pair targeting moieties and methods of making and using such conjugates are described.

Inventors:
 [1];  [2];  [2]
  1. Arlington, MA
  2. Revere, MA
Issue Date:
Research Org.:
Massachusetts General Hospital
OSTI Identifier:
879406
Patent Number(s):
6462070
Application Number:
08/812606
Assignee:
The General Hospital Corporation (Boston, MA)
Patent Classifications (CPCs):
A - HUMAN NECESSITIES A61 - MEDICAL OR VETERINARY SCIENCE A61K - PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
A - HUMAN NECESSITIES A61 - MEDICAL OR VETERINARY SCIENCE A61P - SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
DOE Contract Number:  
FG02-91ER61228
Resource Type:
Patent
Country of Publication:
United States
Language:
English

Citation Formats

Hasan, Tayyaba, Hamblin, Michael R, and Soukos, Nikos. Photosensitizer Conjugates For Pathogen Targeting. United States: N. p., 2002. Web.
Hasan, Tayyaba, Hamblin, Michael R, & Soukos, Nikos. Photosensitizer Conjugates For Pathogen Targeting. United States.
Hasan, Tayyaba, Hamblin, Michael R, and Soukos, Nikos. Tue . "Photosensitizer Conjugates For Pathogen Targeting". United States. https://www.osti.gov/servlets/purl/879406.
@article{osti_879406,
title = {Photosensitizer Conjugates For Pathogen Targeting},
author = {Hasan, Tayyaba and Hamblin, Michael R and Soukos, Nikos},
abstractNote = {Conjugate molecules which include photosensitizer compositions conjugated to non-antibody non-affinity pair targeting moieties and methods of making and using such conjugates are described.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {2002},
month = {10}
}

Works referenced in this record:

Cloning of DNA sequences encoding foreign peptides and their expression in the K88 pili.
journal, January 1989


Screening for receptor ligands using large libraries of peptides linked to the C terminus of the lac repressor.
journal, March 1992


Sensitization of oral bacteria in biofilms to killing by light from a low-power laser
journal, November 1992


New trends in photobiology bactericidal effects of photoactivated porphyrins — An alternative approach to antimicrobial drugs
journal, May 1990


Magainins and the disruption of membrane-linked free-energy transduction
journal, September 1989


Applications of Combinatorial Technologies to Drug Discovery. 1. Background and Peptide Combinatorial Libraries
journal, April 1994


Sensitization of periodontopathogenic bacteria to killing by light from a low-power laser
journal, June 1993


Novel method to extract large amounts of bacteriocins from lactic acid bacteria.
journal, January 1992


The Effects of Porphyrin Structure and Aggregation State on Photosensitized Processes in Aqueous and Micellar Media
journal, November 1986


Enhancement of the chemical and antimicrobial properties of subtilin by site-directed mutagenesis.
journal, December 1992


Directed evolution of a protein: selection of potent neutrophil elastase inhibitors displayed on M13 fusion phage.
journal, March 1992


Peptides on phage: a vast library of peptides for identifying ligands
journal, August 1990


Targeting Recombinant Antibodies to the Surface of Escherichia coli: Fusion to a Peptidoglycan Associated Lipoprotein
journal, December 1991


Inhibitory effects of synthetic histidine-rich peptides on haemagglutination by Bacteroides gingivalis 381
journal, January 1990


Channel formation properties of synthetic pardaxin and analogues
journal, November 1990


Expression of recombinant proteins on the surface of the coagulase-negative bacterium Staphylococcus xylosus.
journal, January 1992


Low-density lipoprotein receptor-deficient mice are protected against lethal endotoxemia and severe gram-negative infections.
journal, March 1996


Dye-mediated bactericidal effect of He-Ne laser irradiation on oral microorganisms
journal, January 1992


Bacteriocins of gram-positive bacteria.
journal, January 1995


Random peptide libraries: a source of specific protein binding molecules
journal, July 1990


In vitro inactivation of bacterial endotoxin by human lipoproteins and apolipoproteins.
journal, January 1992


Sensitization of oral bacteria to killing by low-power laser radiation
journal, August 1992


Searching for peptide ligands with an epitope library
journal, July 1990