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Title: Detection Of Amplified Or Deleted Chromosomal Regions

Abstract

The present invention relates to in situ hybridization methods for the identification of new chromosomal abnormalities associated with various diseases. In particular, it provides probes which are specific to a region of amplification in chromosome 20.

Inventors:
 [1]
  1. (San Fransisco, CA), Pinkel, Daniel (Walnut Creek, CA), Gray, Joe W. (San Fransisco, CA)
Issue Date:
Research Org.:
Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States)
OSTI Identifier:
879266
Patent Number(s):
5633365
Application Number:
08/430984
Assignee:
The Regents of the University of California (Oakland, CA)
Patent Classifications (CPCs):
Y - NEW / CROSS SECTIONAL TECHNOLOGIES Y10 - TECHNICAL SUBJECTS COVERED BY FORMER USPC Y10S - TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
C - CHEMISTRY C12 - BIOCHEMISTRY C12Q - MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS
DOE Contract Number:  
AC03-76SF00098
Resource Type:
Patent
Country of Publication:
United States
Language:
English

Citation Formats

Stokke, Trond. Detection Of Amplified Or Deleted Chromosomal Regions. United States: N. p., 1997. Web.
Stokke, Trond. Detection Of Amplified Or Deleted Chromosomal Regions. United States.
Stokke, Trond. Tue . "Detection Of Amplified Or Deleted Chromosomal Regions". United States. https://www.osti.gov/servlets/purl/879266.
@article{osti_879266,
title = {Detection Of Amplified Or Deleted Chromosomal Regions},
author = {Stokke, Trond},
abstractNote = {The present invention relates to in situ hybridization methods for the identification of new chromosomal abnormalities associated with various diseases. In particular, it provides probes which are specific to a region of amplification in chromosome 20.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {1997},
month = {5}
}

Patent:

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Works referenced in this record:

Complete characterization of a large marker chromosome by reverse and forward chromosome painting
journal, December 1992


Analytical strategies for the use of DNA probes
journal, February 1988


Translocations between two specific human chromosomes detected by three-color “chromosome painting”
journal, January 1993


Detection of amplified DNA sequences by reverse chromosome painting using genomic tumor DNA as probe
journal, February 1993


Fluorescence in situ hybridization with human chromosome-specific libraries: detection of trisomy 21 and translocations of chromosome 4.
journal, December 1988


Detection and mapping of amplified DNA sequences in breast cancer by comparative genomic hybridization.
journal, March 1994


Comparative genomic hybridization for molecular cytogenetic analysis of solid tumors
journal, October 1992


High-resolution mapping of human chromosome 11 by in situ hybridization with cosmid clones
journal, January 1990


In situ hybridisation with fluoresceinated DNA
journal, January 1991


Deletion mapping of chromosomes 8, 10, and 16 in human prostatic carcinoma
journal, May 1991


ERBB2 amplification in breast cancer analyzed by fluorescence in situ hybridization.
journal, June 1992