Position Sequencing By Hybridization
Abstract
Succinoylamino hydroxyethylamino sulfonamide compounds are effective as retroviral protease inhibitors, and in particular as inhibitors of HIV protease.
- Inventors:
-
- Gurnee, IL
- Glencoe, IL
- St. Louis, MO
- Chesterfield, MO
- St. Peters, MO
- Clayton, MO
- Issue Date:
- Research Org.:
- Boston University
- OSTI Identifier:
- 879209
- Patent Number(s):
- 5463104
- Application Number:
- 08/110912
- Assignee:
- G. D. Searle & Co. (Skokie, IL)
- Patent Classifications (CPCs):
-
A - HUMAN NECESSITIES A61 - MEDICAL OR VETERINARY SCIENCE A61K - PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
C - CHEMISTRY C07 - ORGANIC CHEMISTRY C07C - ACYCLIC OR CARBOCYCLIC COMPOUNDS
- DOE Contract Number:
- FG02-93ER61609
- Resource Type:
- Patent
- Country of Publication:
- United States
- Language:
- English
Citation Formats
Vazquez, Michael L, Mueller, Richard A, Talley, John J, Getman, Daniel, DeCrescenzo, Gary A, and Freskos, John N. Position Sequencing By Hybridization. United States: N. p., 1995.
Web.
Vazquez, Michael L, Mueller, Richard A, Talley, John J, Getman, Daniel, DeCrescenzo, Gary A, & Freskos, John N. Position Sequencing By Hybridization. United States.
Vazquez, Michael L, Mueller, Richard A, Talley, John J, Getman, Daniel, DeCrescenzo, Gary A, and Freskos, John N. Tue .
"Position Sequencing By Hybridization". United States. https://www.osti.gov/servlets/purl/879209.
@article{osti_879209,
title = {Position Sequencing By Hybridization},
author = {Vazquez, Michael L and Mueller, Richard A and Talley, John J and Getman, Daniel and DeCrescenzo, Gary A and Freskos, John N},
abstractNote = {Succinoylamino hydroxyethylamino sulfonamide compounds are effective as retroviral protease inhibitors, and in particular as inhibitors of HIV protease.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {1995},
month = {10}
}
Works referenced in this record:
A synthetic HIV-1 protease inhibitor with antiviral activity arrests HIV-like particle maturation
journal, January 1990
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Design, activity, and 2.8 A crystal structure of a C2 symmetric inhibitor complexed to HIV-1 protease
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- Science, Vol. 249, Issue 4968
Inhibition of HIV-1 protease in infected T-lymphocytes by synthetic peptide analogues
journal, January 1990
- Meek, Thomas D.; Lambert, Dennis M.; Dreyer, Geoffrey B.
- Nature, Vol. 343, Issue 6253
Rational design of peptide-based HIV proteinase inhibitors
journal, April 1990
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Novel renin inhibitors containing analogs of statine retro-inverted at the C-termini. Specificity at the P2 histidine site
journal, July 1987
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- Journal of Medicinal Chemistry, Vol. 30, Issue 7
Sequence specificity of retroviral proteases
journal, August 1987
- Pear, Laurence H.; Taylo, William R.
- Nature, Vol. 328, Issue 6130