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Title: Position Sequencing By Hybridization

Abstract

Succinoylamino hydroxyethylamino sulfonamide compounds are effective as retroviral protease inhibitors, and in particular as inhibitors of HIV protease.

Inventors:
 [1];  [2];  [3];  [4];  [5];  [6]
  1. Gurnee, IL
  2. Glencoe, IL
  3. St. Louis, MO
  4. Chesterfield, MO
  5. St. Peters, MO
  6. Clayton, MO
Issue Date:
Research Org.:
Boston University
OSTI Identifier:
879209
Patent Number(s):
5463104
Application Number:
08/110912
Assignee:
G. D. Searle & Co. (Skokie, IL)
Patent Classifications (CPCs):
A - HUMAN NECESSITIES A61 - MEDICAL OR VETERINARY SCIENCE A61K - PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
C - CHEMISTRY C07 - ORGANIC CHEMISTRY C07C - ACYCLIC OR CARBOCYCLIC COMPOUNDS
DOE Contract Number:  
FG02-93ER61609
Resource Type:
Patent
Country of Publication:
United States
Language:
English

Citation Formats

Vazquez, Michael L, Mueller, Richard A, Talley, John J, Getman, Daniel, DeCrescenzo, Gary A, and Freskos, John N. Position Sequencing By Hybridization. United States: N. p., 1995. Web.
Vazquez, Michael L, Mueller, Richard A, Talley, John J, Getman, Daniel, DeCrescenzo, Gary A, & Freskos, John N. Position Sequencing By Hybridization. United States.
Vazquez, Michael L, Mueller, Richard A, Talley, John J, Getman, Daniel, DeCrescenzo, Gary A, and Freskos, John N. Tue . "Position Sequencing By Hybridization". United States. https://www.osti.gov/servlets/purl/879209.
@article{osti_879209,
title = {Position Sequencing By Hybridization},
author = {Vazquez, Michael L and Mueller, Richard A and Talley, John J and Getman, Daniel and DeCrescenzo, Gary A and Freskos, John N},
abstractNote = {Succinoylamino hydroxyethylamino sulfonamide compounds are effective as retroviral protease inhibitors, and in particular as inhibitors of HIV protease.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {1995},
month = {10}
}

Works referenced in this record:

A synthetic HIV-1 protease inhibitor with antiviral activity arrests HIV-like particle maturation
journal, January 1990


Design, activity, and 2.8 A crystal structure of a C2 symmetric inhibitor complexed to HIV-1 protease
journal, August 1990


Inhibition of HIV-1 protease in infected T-lymphocytes by synthetic peptide analogues
journal, January 1990


Ro-31-8959/003
journal, January 1991


Rational design of peptide-based HIV proteinase inhibitors
journal, April 1990


Novel renin inhibitors containing analogs of statine retro-inverted at the C-termini. Specificity at the P2 histidine site
journal, July 1987


Sequence specificity of retroviral proteases
journal, August 1987