skip to main content
DOE Patents title logo U.S. Department of Energy
Office of Scientific and Technical Information

Title: Flowmeter for pressure-driven chromatography systems

Abstract

A flowmeter for accurately measuring the flowrate of fluids in high pressure chromatography systems. The flowmeter is a porous bed of a material, the porous bed having a porosity in the range of about 0.1 to 0.6 and a pore size in the range of about 50 nm to 1 .mu.m, disposed between a high pressure pumping means and a chromatography column. The flowmeter is provided with pressure measuring means at both the inlet and outlet of the porous bed for measuring the pressure drop through the porous bed. This flowmeter system provides not only the ability to measure accurately flowrates in the range of .mu.L/min to nL/min but also to provide a signal that can be used for a servo loop or feedback control system for high pressure pumping systems.

Inventors:
 [1];  [1]
  1. (Livermore, CA)
Issue Date:
Research Org.:
SANDIA CORP
OSTI Identifier:
875105
Patent Number(s):
6532802
Assignee:
Sandia National Laboratories (Livermore, CA) SNL
DOE Contract Number:  
AC04-94AL85000
Resource Type:
Patent
Country of Publication:
United States
Language:
English
Subject:
flowmeter; pressure-driven; chromatography; systems; accurately; measuring; flowrate; fluids; pressure; porous; bed; material; porosity; range; 01; 06; pore; size; 50; nm; mum; disposed; pumping; means; column; provided; inlet; outlet; drop; provides; ability; measure; flowrates; mulmin; nlmin; provide; signal; servo; loop; feedback; control; pore size; chromatography column; pressure pump; porous bed; /73/210/

Citation Formats

Paul, Phillip H., and Arnold, Don W. Flowmeter for pressure-driven chromatography systems. United States: N. p., 2003. Web.
Paul, Phillip H., & Arnold, Don W. Flowmeter for pressure-driven chromatography systems. United States.
Paul, Phillip H., and Arnold, Don W. Wed . "Flowmeter for pressure-driven chromatography systems". United States. https://www.osti.gov/servlets/purl/875105.
@article{osti_875105,
title = {Flowmeter for pressure-driven chromatography systems},
author = {Paul, Phillip H. and Arnold, Don W.},
abstractNote = {A flowmeter for accurately measuring the flowrate of fluids in high pressure chromatography systems. The flowmeter is a porous bed of a material, the porous bed having a porosity in the range of about 0.1 to 0.6 and a pore size in the range of about 50 nm to 1 .mu.m, disposed between a high pressure pumping means and a chromatography column. The flowmeter is provided with pressure measuring means at both the inlet and outlet of the porous bed for measuring the pressure drop through the porous bed. This flowmeter system provides not only the ability to measure accurately flowrates in the range of .mu.L/min to nL/min but also to provide a signal that can be used for a servo loop or feedback control system for high pressure pumping systems.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {2003},
month = {1}
}

Patent:

Save / Share: