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Title: Therapeutic tin-117m compositions

Abstract

The invention provides a method for the palliation of bone pain due to cancer by the administration of a unique dosage of a tin-117m (Sn-117m) stannic chelate complex in a pharmaceutically acceptable composition. In addition, the invention provides a method for simultaneous palliation of bone pain and radiotherapy in cancer patients using compositions containing Sn-117m chelates. The invention also provides a method for palliating bone pain in cancer patients using Sn-117m-containing compositions and monitoring patient status by imaging the distribution of the Sn-117m in the patients. Also provided are pharmaceutically acceptable compositions containing Sn-117m chelate complexes for the palliation of bone pain in cancer patients.

Inventors:
 [1];  [2];  [3];  [1]
  1. Setauket, NY
  2. Middle Island, NY
  3. Stony Brook, NY
Issue Date:
Research Org.:
Associated Universities, Inc., Upton, NY (United States)
OSTI Identifier:
875037
Patent Number(s):
6517810
Assignee:
Brookhaven Science Associates LLC (Upton, NY)
DOE Contract Number:  
AC02-76CH00016
Resource Type:
Patent
Country of Publication:
United States
Language:
English
Subject:
therapeutic; tin-117m; compositions; provides; method; palliation; bone; pain; due; cancer; administration; unique; dosage; sn-117m; stannic; chelate; complex; pharmaceutically; acceptable; composition; addition; simultaneous; radiotherapy; patients; containing; chelates; palliating; sn-117m-containing; monitoring; patient; status; imaging; distribution; provided; complexes; pharmaceutically acceptable; /424/

Citation Formats

Srivastava, Suresh C, Meinken, George E, Mausner, Leonard F, and Atkins, Harold L. Therapeutic tin-117m compositions. United States: N. p., 2003. Web.
Srivastava, Suresh C, Meinken, George E, Mausner, Leonard F, & Atkins, Harold L. Therapeutic tin-117m compositions. United States.
Srivastava, Suresh C, Meinken, George E, Mausner, Leonard F, and Atkins, Harold L. Wed . "Therapeutic tin-117m compositions". United States. https://www.osti.gov/servlets/purl/875037.
@article{osti_875037,
title = {Therapeutic tin-117m compositions},
author = {Srivastava, Suresh C and Meinken, George E and Mausner, Leonard F and Atkins, Harold L},
abstractNote = {The invention provides a method for the palliation of bone pain due to cancer by the administration of a unique dosage of a tin-117m (Sn-117m) stannic chelate complex in a pharmaceutically acceptable composition. In addition, the invention provides a method for simultaneous palliation of bone pain and radiotherapy in cancer patients using compositions containing Sn-117m chelates. The invention also provides a method for palliating bone pain in cancer patients using Sn-117m-containing compositions and monitoring patient status by imaging the distribution of the Sn-117m in the patients. Also provided are pharmaceutically acceptable compositions containing Sn-117m chelate complexes for the palliation of bone pain in cancer patients.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {2003},
month = {1}
}

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Works referenced in this record:

Biodistribution of Sn-117m(4+)DTPA for palliative therapy of painful osseous metastases.
journal, January 1993