Agouti polynucleotide compositions and methods of use
Abstract
Disclosed are methods and compositions comprising novel agouti polypeptides and the polynucleotides which encode them. Also disclosed are DNA segments encoding these proteins derived from human and murine cell lines, and the use of these polynucleotides and polypeptides in a variety of diagnostic and therapeutic applications. Methods, compositions, kits, and devices are also provided for identifying compounds which are inhibitors of agouti activity, and for altering fatty acid synthetase activity and intracellular calcium levels in transformed cells.
- Inventors:
-
- (Orinda, CA)
- (Lakewood, OH)
- (Kingston, TN)
- Issue Date:
- Research Org.:
- Oak Ridge National Laboratory (ORNL), Oak Ridge, TN
- OSTI Identifier:
- 875024
- Patent Number(s):
- 6514747
- Application Number:
- 09/781,811
- Assignee:
- UT-Battelle, LLC (Oak Ridge, TN) ORNL
- Resource Type:
- Patent
- Country of Publication:
- United States
- Language:
- English
- Subject:
- agouti; polynucleotide; compositions; methods; disclosed; comprising; novel; polypeptides; polynucleotides; encode; dna; segments; encoding; proteins; derived; human; murine; cell; lines; variety; diagnostic; therapeutic; applications; kits; devices; provided; identifying; compounds; inhibitors; activity; altering; fatty; acid; synthetase; intracellular; calcium; levels; transformed; cells; fatty acid; /435/999/
Citation Formats
Woychik, Richard P., Bultman, Scott J., and Michaud, Edward J. Agouti polynucleotide compositions and methods of use. United States: N. p., 2003.
Web.
Woychik, Richard P., Bultman, Scott J., & Michaud, Edward J. Agouti polynucleotide compositions and methods of use. United States.
Woychik, Richard P., Bultman, Scott J., and Michaud, Edward J. Tue .
"Agouti polynucleotide compositions and methods of use". United States. https://www.osti.gov/servlets/purl/875024.
@article{osti_875024,
title = {Agouti polynucleotide compositions and methods of use},
author = {Woychik, Richard P. and Bultman, Scott J. and Michaud, Edward J.},
abstractNote = {Disclosed are methods and compositions comprising novel agouti polypeptides and the polynucleotides which encode them. Also disclosed are DNA segments encoding these proteins derived from human and murine cell lines, and the use of these polynucleotides and polypeptides in a variety of diagnostic and therapeutic applications. Methods, compositions, kits, and devices are also provided for identifying compounds which are inhibitors of agouti activity, and for altering fatty acid synthetase activity and intracellular calcium levels in transformed cells.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {2003},
month = {2}
}
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