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Title: Cytochrome b5 gene and protein of Candida tropicalis and methods relating thereto

Abstract

A novel gene has been isolated which encodes cytochrome b5 (CYTb5) protein of the .omega.-hydroxylase complex of C. tropicalis 20336. Vectors including this gene, and transformed host cells are provided. Methods of increasing the production of a CYTb5 protein are also provided which involve transforming a host cell with a gene encoding this protein and culturing the cells. Methods of increasing the production of a dicarboxylic acid are also provided which involve increasing in the host cell the number of genes encoding this protein.

Inventors:
 [1];  [2];  [3]
  1. (Fort Thomas, KY)
  2. (Westfield, IN)
  3. (Cincinnati, OH)
Issue Date:
Research Org.:
GE CORPORATE R & D
OSTI Identifier:
874978
Patent Number(s):
6503734
Assignee:
Cognis Corporation (Gulph Mills, PA) GFO
DOE Contract Number:  
FC36-95GO10099
Resource Type:
Patent
Country of Publication:
United States
Language:
English
Subject:
cytochrome; b5; protein; candida; tropicalis; methods; relating; novel; isolated; encodes; cytb5; omega-hydroxylase; complex; 20336; vectors; including; transformed; host; cells; provided; increasing; production; involve; transforming; cell; encoding; culturing; dicarboxylic; acid; genes; host cell; /435/999/

Citation Formats

Craft, David L., Madduri, Krishna M., and Loper, John C. Cytochrome b5 gene and protein of Candida tropicalis and methods relating thereto. United States: N. p., 2003. Web.
Craft, David L., Madduri, Krishna M., & Loper, John C. Cytochrome b5 gene and protein of Candida tropicalis and methods relating thereto. United States.
Craft, David L., Madduri, Krishna M., and Loper, John C. Wed . "Cytochrome b5 gene and protein of Candida tropicalis and methods relating thereto". United States. https://www.osti.gov/servlets/purl/874978.
@article{osti_874978,
title = {Cytochrome b5 gene and protein of Candida tropicalis and methods relating thereto},
author = {Craft, David L. and Madduri, Krishna M. and Loper, John C.},
abstractNote = {A novel gene has been isolated which encodes cytochrome b5 (CYTb5) protein of the .omega.-hydroxylase complex of C. tropicalis 20336. Vectors including this gene, and transformed host cells are provided. Methods of increasing the production of a CYTb5 protein are also provided which involve transforming a host cell with a gene encoding this protein and culturing the cells. Methods of increasing the production of a dicarboxylic acid are also provided which involve increasing in the host cell the number of genes encoding this protein.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {2003},
month = {1}
}

Patent:

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