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Title: Electrochemical methods for generation of a biological proton motive force and pyridine nucleotide cofactor regeneration

Abstract

Disclosed are methods using neutral red to mediate the interconversion of chemical and electrical energy. Electrically reduced neutral red has been found to promote cell growth and formation of reduced products by reversibly increasing the ratio of the reduced:oxidized forms of NAD(H) or NADP(H). Electrically reduced neutral red is able to serve as the sole source of reducing power for microbial, cell growth. Neutral red is also able to promote conversion of chemical energy to electrical energy by facilitating the transfer of electrons from microbial reducing power to a fuel cell cathode.

Inventors:
 [1];  [2];  [3]
  1. (Okemos, MI)
  2. (Lansing, MI)
  3. (Lexington, KY)
Issue Date:
Research Org.:
Michigan State University (East Lansing, MI)
OSTI Identifier:
874944
Patent Number(s):
6495023
Assignee:
Michigan State University (East Lansing, MI) CHO
DOE Contract Number:  
FG02-93ER20108
Resource Type:
Patent
Country of Publication:
United States
Language:
English
Subject:
electrochemical; methods; generation; biological; proton; motive; force; pyridine; nucleotide; cofactor; regeneration; disclosed; neutral; mediate; interconversion; chemical; electrical; energy; electrically; reduced; found; promote; cell; growth; formation; products; reversibly; increasing; ratio; reducedoxidized; forms; nadh; nadph; serve; sole; source; reducing; power; microbial; conversion; facilitating; transfer; electrons; fuel; cathode; fuel cell; electrical energy; chemical energy; electrochemical method; motive force; /205/

Citation Formats

Zeikus, Gregory J., Shin, Hyoun S., and Jain, Mahendra K. Electrochemical methods for generation of a biological proton motive force and pyridine nucleotide cofactor regeneration. United States: N. p., 2002. Web.
Zeikus, Gregory J., Shin, Hyoun S., & Jain, Mahendra K. Electrochemical methods for generation of a biological proton motive force and pyridine nucleotide cofactor regeneration. United States.
Zeikus, Gregory J., Shin, Hyoun S., and Jain, Mahendra K. Tue . "Electrochemical methods for generation of a biological proton motive force and pyridine nucleotide cofactor regeneration". United States. https://www.osti.gov/servlets/purl/874944.
@article{osti_874944,
title = {Electrochemical methods for generation of a biological proton motive force and pyridine nucleotide cofactor regeneration},
author = {Zeikus, Gregory J. and Shin, Hyoun S. and Jain, Mahendra K.},
abstractNote = {Disclosed are methods using neutral red to mediate the interconversion of chemical and electrical energy. Electrically reduced neutral red has been found to promote cell growth and formation of reduced products by reversibly increasing the ratio of the reduced:oxidized forms of NAD(H) or NADP(H). Electrically reduced neutral red is able to serve as the sole source of reducing power for microbial, cell growth. Neutral red is also able to promote conversion of chemical energy to electrical energy by facilitating the transfer of electrons from microbial reducing power to a fuel cell cathode.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {2002},
month = {1}
}

Patent:

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