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Title: Laser and acoustic lens for lithotripsy

Abstract

An acoustic focusing device whose acoustic waves are generated by laser radiation through an optical fiber. The acoustic energy is capable of efficient destruction of renal and biliary calculi and deliverable to the site of the calculi via an endoscopic procedure. The device includes a transducer tip attached to the distal end of an optical fiber through which laser energy is directed. The transducer tip encapsulates an exogenous absorbing dye. Under proper irradiation conditions (high absorbed energy density, short pulse duration) a stress wave is produced via thermoelastic expansion of the absorber for the destruction of the calculi. The transducer tip can be configured into an acoustic lens such that the transmitted acoustic wave is shaped or focused. Also, compressive stress waves can be reflected off a high density/low density interface to invert the compressive wave into a tensile stress wave, and tensile stresses may be more effective in some instances in disrupting material as most materials are weaker in tension than compression. Estimations indicate that stress amplitudes provided by this device can be magnified more than 100 times, greatly improving the efficiency of optical energy for targeted material destruction.

Inventors:
 [1];  [2];  [3];  [1];  [4];  [4]
  1. Livermore, CA
  2. San Ramon, CA
  3. Orinda, CA
  4. Pleasanton, CA
Issue Date:
Research Org.:
Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States)
OSTI Identifier:
874928
Patent Number(s):
6491685
Assignee:
The Regents of the University of California (Oakland, CA)
Patent Classifications (CPCs):
A - HUMAN NECESSITIES A61 - MEDICAL OR VETERINARY SCIENCE A61B - DIAGNOSIS
DOE Contract Number:  
W-7405-ENG-48
Resource Type:
Patent
Country of Publication:
United States
Language:
English
Subject:
laser; acoustic; lens; lithotripsy; focusing; device; waves; generated; radiation; optical; fiber; energy; capable; efficient; destruction; renal; biliary; calculi; deliverable; site; via; endoscopic; procedure; transducer; tip; attached; distal; directed; encapsulates; exogenous; absorbing; dye; proper; irradiation; conditions; absorbed; density; pulse; duration; stress; wave; produced; thermoelastic; expansion; absorber; configured; transmitted; shaped; focused; compressive; reflected; densitylow; interface; invert; tensile; stresses; effective; instances; disrupting; material; materials; weaker; tension; compression; estimations; indicate; amplitudes; provided; magnified; 100; times; greatly; improving; efficiency; targeted; optical fiber; laser radiation; acoustic wave; compressive stress; /606/

Citation Formats

Visuri, Steven R, Makarewicz, Anthony J, London, Richard A, Benett, William J, Krulevitch, Peter, and Da Silva, Luiz B. Laser and acoustic lens for lithotripsy. United States: N. p., 2002. Web.
Visuri, Steven R, Makarewicz, Anthony J, London, Richard A, Benett, William J, Krulevitch, Peter, & Da Silva, Luiz B. Laser and acoustic lens for lithotripsy. United States.
Visuri, Steven R, Makarewicz, Anthony J, London, Richard A, Benett, William J, Krulevitch, Peter, and Da Silva, Luiz B. Tue . "Laser and acoustic lens for lithotripsy". United States. https://www.osti.gov/servlets/purl/874928.
@article{osti_874928,
title = {Laser and acoustic lens for lithotripsy},
author = {Visuri, Steven R and Makarewicz, Anthony J and London, Richard A and Benett, William J and Krulevitch, Peter and Da Silva, Luiz B},
abstractNote = {An acoustic focusing device whose acoustic waves are generated by laser radiation through an optical fiber. The acoustic energy is capable of efficient destruction of renal and biliary calculi and deliverable to the site of the calculi via an endoscopic procedure. The device includes a transducer tip attached to the distal end of an optical fiber through which laser energy is directed. The transducer tip encapsulates an exogenous absorbing dye. Under proper irradiation conditions (high absorbed energy density, short pulse duration) a stress wave is produced via thermoelastic expansion of the absorber for the destruction of the calculi. The transducer tip can be configured into an acoustic lens such that the transmitted acoustic wave is shaped or focused. Also, compressive stress waves can be reflected off a high density/low density interface to invert the compressive wave into a tensile stress wave, and tensile stresses may be more effective in some instances in disrupting material as most materials are weaker in tension than compression. Estimations indicate that stress amplitudes provided by this device can be magnified more than 100 times, greatly improving the efficiency of optical energy for targeted material destruction.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {2002},
month = {1}
}

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