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Title: Chemical sensor system

Abstract

An implantable chemical sensor system for medical applications is described which permits selective recognition of an analyte using an expandable biocompatible sensor, such as a polymer, that undergoes a dimensional change in the presence of the analyte. The expandable polymer is incorporated into an electronic circuit component that changes its properties (e.g., frequency) when the polymer changes dimension. As the circuit changes its characteristics, an external interrogator transmits a signal transdermally to the transducer, and the concentration of the analyte is determined from the measured changes in the circuit. This invention may be used for minimally invasive monitoring of blood glucose levels in diabetic patients.

Inventors:
 [1];  [2];  [3];  [4];  [5]
  1. (Pleasanton, CA)
  2. (Modesto, CA)
  3. (Oakland, CA)
  4. (Walnut Creek, CA)
  5. (Berkeley, CA)
Issue Date:
Research Org.:
Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States)
OSTI Identifier:
874879
Patent Number(s):
6480730
Assignee:
The Regents of the University of California (Oakland, CA) LLNL
DOE Contract Number:  
W-7405-ENG-48
Resource Type:
Patent
Country of Publication:
United States
Language:
English
Subject:
chemical; sensor; implantable; medical; applications; described; permits; selective; recognition; analyte; expandable; biocompatible; polymer; undergoes; dimensional; change; presence; incorporated; electronic; circuit; component; changes; properties; frequency; dimension; characteristics; external; interrogator; transmits; signal; transdermally; transducer; concentration; determined; measured; minimally; invasive; monitoring; blood; glucose; levels; diabetic; patients; medical applications; permits selective; dimensional change; /600/

Citation Formats

Darrow, Christopher B., Satcher, Jr., Joe H., Lane, Stephen M., Lee, Abraham P., and Wang, Amy W. Chemical sensor system. United States: N. p., 2002. Web.
Darrow, Christopher B., Satcher, Jr., Joe H., Lane, Stephen M., Lee, Abraham P., & Wang, Amy W. Chemical sensor system. United States.
Darrow, Christopher B., Satcher, Jr., Joe H., Lane, Stephen M., Lee, Abraham P., and Wang, Amy W. Tue . "Chemical sensor system". United States. https://www.osti.gov/servlets/purl/874879.
@article{osti_874879,
title = {Chemical sensor system},
author = {Darrow, Christopher B. and Satcher, Jr., Joe H. and Lane, Stephen M. and Lee, Abraham P. and Wang, Amy W.},
abstractNote = {An implantable chemical sensor system for medical applications is described which permits selective recognition of an analyte using an expandable biocompatible sensor, such as a polymer, that undergoes a dimensional change in the presence of the analyte. The expandable polymer is incorporated into an electronic circuit component that changes its properties (e.g., frequency) when the polymer changes dimension. As the circuit changes its characteristics, an external interrogator transmits a signal transdermally to the transducer, and the concentration of the analyte is determined from the measured changes in the circuit. This invention may be used for minimally invasive monitoring of blood glucose levels in diabetic patients.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {2002},
month = {1}
}

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