Porous polymer media
Abstract
Highly crosslinked monolithic porous polymer materials for chromatographic applications. By using solvent compositions that provide not only for polymerization of acrylate monomers in such a fashion that a porous polymer network is formed prior to phase separation but also for exchanging the polymerization solvent for a running buffer using electroosmotic flow, the need for high pressure purging is eliminated. The polymer materials have been shown to be an effective capillary electrochromatographic separations medium at lower field strengths than conventional polymer media. Further, because of their highly crosslinked nature these polymer materials are structurally stable in a wide range of organic and aqueous solvents and over a pH range of 2-12.
- Inventors:
-
- Livermore, CA
- Issue Date:
- Research Org.:
- Sandia National Laboratories (SNL), Albuquerque, NM, and Livermore, CA (United States)
- OSTI Identifier:
- 874843
- Patent Number(s):
- 6472443
- Assignee:
- Sandia National Laboratories (Livermore, CA)
- Patent Classifications (CPCs):
-
B - PERFORMING OPERATIONS B01 - PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL B01D - SEPARATION
B - PERFORMING OPERATIONS B01 - PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL B01J - CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY
- DOE Contract Number:
- EAC0494AL85000
- Resource Type:
- Patent
- Country of Publication:
- United States
- Language:
- English
- Subject:
- porous; polymer; media; highly; crosslinked; monolithic; materials; chromatographic; applications; solvent; compositions; provide; polymerization; acrylate; monomers; fashion; network; formed; prior; phase; separation; exchanging; running; buffer; electroosmotic; flow; pressure; purging; eliminated; shown; effective; capillary; electrochromatographic; separations; medium; field; strengths; conventional; nature; structurally; stable; wide; range; organic; aqueous; solvents; ph; 2-12; wide range; polymer material; solvent composition; porous polymer; /521/428/
Citation Formats
Shepodd, Timothy J. Porous polymer media. United States: N. p., 2002.
Web.
Shepodd, Timothy J. Porous polymer media. United States.
Shepodd, Timothy J. Tue .
"Porous polymer media". United States. https://www.osti.gov/servlets/purl/874843.
@article{osti_874843,
title = {Porous polymer media},
author = {Shepodd, Timothy J},
abstractNote = {Highly crosslinked monolithic porous polymer materials for chromatographic applications. By using solvent compositions that provide not only for polymerization of acrylate monomers in such a fashion that a porous polymer network is formed prior to phase separation but also for exchanging the polymerization solvent for a running buffer using electroosmotic flow, the need for high pressure purging is eliminated. The polymer materials have been shown to be an effective capillary electrochromatographic separations medium at lower field strengths than conventional polymer media. Further, because of their highly crosslinked nature these polymer materials are structurally stable in a wide range of organic and aqueous solvents and over a pH range of 2-12.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {Tue Jan 01 00:00:00 EST 2002},
month = {Tue Jan 01 00:00:00 EST 2002}
}
Works referenced in this record:
Macroporous Polyacrylamide/Poly(ethylene glycol) Matrixes as Stationary Phases in Capillary Electrochromatography
journal, November 1997
- Palm, Anders; Novotny, Milos V.
- Analytical Chemistry, Vol. 69, Issue 22
Electroosmosis- and Pressure-Driven Chromatography in Chips Using Continuous Beds
journal, January 2000
- Ericson, Christer; Holm, Johan; Ericson, Thomas
- Analytical Chemistry, Vol. 72, Issue 1