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Title: Water-soluble luminescent quantum dots and biomolecular conjugates thereof and related compositions and method of use

Abstract

The present invention provides a water-soluble luminescent quantum dot, a biomolecular conjugate thereof and a composition comprising such a quantum dot or conjugate. Additionally, the present invention provides a method of obtaining a luminescent quantum dot, a method of making a biomolecular conjugate thereof, and methods of using a biomolecular conjugate for ultrasensitive nonisotopic detection in vitro and in vivo.

Inventors:
 [1];  [1];  [2]
  1. Bloomington, IN
  2. Los Alamos, NM
Issue Date:
Research Org.:
Indiana Univ., Bloomington, IN (United States)
OSTI Identifier:
874824
Patent Number(s):
6468808
Assignee:
Advanced Research and Technology Institute, Inc. (Indianapolis, IN)
Patent Classifications (CPCs):
B - PERFORMING OPERATIONS B82 - NANOTECHNOLOGY B82Y - SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES
C - CHEMISTRY C12 - BIOCHEMISTRY C12Q - MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS
DOE Contract Number:  
FG02-98ER14873
Resource Type:
Patent
Country of Publication:
United States
Language:
English
Subject:
water-soluble; luminescent; quantum; dots; biomolecular; conjugates; related; compositions; method; provides; dot; conjugate; composition; comprising; additionally; obtaining; methods; ultrasensitive; nonisotopic; detection; vitro; vivo; /436/257/420/428/430/435/

Citation Formats

Nie, Shuming, Chan, Warren C. W., and Emory, Steven R. Water-soluble luminescent quantum dots and biomolecular conjugates thereof and related compositions and method of use. United States: N. p., 2002. Web.
Nie, Shuming, Chan, Warren C. W., & Emory, Steven R. Water-soluble luminescent quantum dots and biomolecular conjugates thereof and related compositions and method of use. United States.
Nie, Shuming, Chan, Warren C. W., and Emory, Steven R. Tue . "Water-soluble luminescent quantum dots and biomolecular conjugates thereof and related compositions and method of use". United States. https://www.osti.gov/servlets/purl/874824.
@article{osti_874824,
title = {Water-soluble luminescent quantum dots and biomolecular conjugates thereof and related compositions and method of use},
author = {Nie, Shuming and Chan, Warren C. W. and Emory, Steven R},
abstractNote = {The present invention provides a water-soluble luminescent quantum dot, a biomolecular conjugate thereof and a composition comprising such a quantum dot or conjugate. Additionally, the present invention provides a method of obtaining a luminescent quantum dot, a method of making a biomolecular conjugate thereof, and methods of using a biomolecular conjugate for ultrasensitive nonisotopic detection in vitro and in vivo.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {2002},
month = {1}
}

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