skip to main content
DOE Patents title logo U.S. Department of Energy
Office of Scientific and Technical Information

Title: Surface plasmon resonance spectroscopy sensor and methods for using same

Abstract

A surface plasmon resonance ("SPR") probe with a detachable sensor head and system and methods for using the same in various applications is described. The SPR probe couples fiber optic cables directly to an SPR substrate that has a generally planar input surface and a generally curved reflecting surface, such as a substrate formed as a hemisphere. Forming the SPR probe in this manner allows the probe to be miniaturized and operate without the need for high precision, expensive and bulky collimating or focusing optics. Additionally, the curved reflecting surface of the substrate can be coated with one or multiple patches of sensing medium to allow the probe to detect for multiple analytes of interest or to provide multiple readings for comparison and higher precision. Specific applications for the probe are disclosed, including extremely high sensitive relative humidity and dewpoint detection for, e.g., moisture-sensitive environment such as volatile chemical reactions. The SPR probe disclosed operates with a large dynamic range and provides extremely high quality spectra despite being robust enough for field deployment and readily manufacturable.

Inventors:
 [1];  [2]
  1. N. Augusta, SC
  2. Evans, GA
Issue Date:
Research Org.:
Savannah River Site (SRS), Aiken, SC (United States)
OSTI Identifier:
874810
Patent Number(s):
6466323
Assignee:
Westinghouse Savannah River Company, L.L.C. (Aiken, SC)
Patent Classifications (CPCs):
G - PHYSICS G01 - MEASURING G01N - INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
DOE Contract Number:  
AC09-96SR18500
Resource Type:
Patent
Country of Publication:
United States
Language:
English
Subject:
surface; plasmon; resonance; spectroscopy; sensor; methods; spr; probe; detachable; head; applications; described; couples; fiber; optic; cables; directly; substrate; planar; input; curved; reflecting; formed; hemisphere; forming; manner; allows; miniaturized; operate; precision; expensive; bulky; collimating; focusing; optics; additionally; coated; multiple; patches; sensing; medium; allow; detect; analytes; provide; readings; comparison; specific; disclosed; including; extremely; sensitive; humidity; dewpoint; detection; moisture-sensitive; environment; volatile; chemical; reactions; operates; dynamic; range; provides; quality; spectra; despite; robust; field; deployment; readily; manufacturable; fiber optic; reflecting surface; chemical reaction; sensor head; resonance spectroscopy; /356/

Citation Formats

Anderson, Brian Benjamin, and Nave, Stanley Eugene. Surface plasmon resonance spectroscopy sensor and methods for using same. United States: N. p., 2002. Web.
Anderson, Brian Benjamin, & Nave, Stanley Eugene. Surface plasmon resonance spectroscopy sensor and methods for using same. United States.
Anderson, Brian Benjamin, and Nave, Stanley Eugene. Tue . "Surface plasmon resonance spectroscopy sensor and methods for using same". United States. https://www.osti.gov/servlets/purl/874810.
@article{osti_874810,
title = {Surface plasmon resonance spectroscopy sensor and methods for using same},
author = {Anderson, Brian Benjamin and Nave, Stanley Eugene},
abstractNote = {A surface plasmon resonance ("SPR") probe with a detachable sensor head and system and methods for using the same in various applications is described. The SPR probe couples fiber optic cables directly to an SPR substrate that has a generally planar input surface and a generally curved reflecting surface, such as a substrate formed as a hemisphere. Forming the SPR probe in this manner allows the probe to be miniaturized and operate without the need for high precision, expensive and bulky collimating or focusing optics. Additionally, the curved reflecting surface of the substrate can be coated with one or multiple patches of sensing medium to allow the probe to detect for multiple analytes of interest or to provide multiple readings for comparison and higher precision. Specific applications for the probe are disclosed, including extremely high sensitive relative humidity and dewpoint detection for, e.g., moisture-sensitive environment such as volatile chemical reactions. The SPR probe disclosed operates with a large dynamic range and provides extremely high quality spectra despite being robust enough for field deployment and readily manufacturable.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {2002},
month = {1}
}

Patent:

Save / Share:

Works referenced in this record:

Optimal linear data analysis for surface plasmon resonance biosensors
journal, January 1999


Surface plasmon resonance of colloidal Au-modified gold films
journal, January 1999


Surface plasmon resonance sensors: review
journal, January 1999


Compact surface plasmon resonance-transducers with spectral readout for biosensing applications
journal, January 1999


A surface plasmon resonance sensor probe based on retro-reflection
journal, December 1997


Enhanced sensitivity of wavelength modulated surface plasmon resonance devices using dispersion from a dye solution
journal, January 1999


On the sensitivity of surface plasmon resonance sensors with spectral interrogation
journal, June 1997


An intrinsically protein-resistant surface plasmon resonance biosensor based upon a RF-plasma-deposited thin film
journal, January 1999


Surface plasmon resonance sensors based on diffraction gratings and prism couplers: sensitivity comparison
journal, January 1999


Theory and modelling of optical waveguide sensors utilising surface plasmon resonance
journal, January 1999


Performance comparison between high and low resolution spectrophotometers used in a white light surface plasmon resonance sensor
journal, January 1999


The detection of phenols in water using a surface plasmon resonance system with specific receptors
journal, August 1998


Integrated analytical sensors: the use of the TISPR-1 as a biosensor
journal, January 1999


Novel polarization control scheme for spectral surface plasmon resonance sensors
journal, August 1998


A comparative study of spectral and angle-dependent SPR devices in biological applications
journal, August 1998


Miniaturization of fiber optic surface plasmon resonance sensor
journal, August 1998


Development of a surface plasmon resonance sensor for commercial applications
journal, March 1997


Novel surface plasmon resonance sensor chip functionalized with organic silica compounds for antibody attachment
journal, July 1998


Construction of biosensors using a gold-binding polypeptide and a miniature integrated surface plasmon resonance sensor
journal, November 1998