Electrokinetic concentration of charged molecules
Abstract
A method for separating and concentrating charged species from uncharged or neutral species regardless of size differential. The method uses reversible electric field induced retention of charged species, that can include molecules and molecular aggregates such as dimers, polymers, multimers, colloids, micelles, and liposomes, in volumes and on surfaces of porous materials. The retained charged species are subsequently quantitatively removed from the porous material by a pressure driven flow that passes through the retention volume and is independent of direction thus, a multi-directional flow field is not required. Uncharged species pass through the system unimpeded thus effecting a complete separation of charged and uncharged species and making possible concentration factors greater than 1000-fold.
- Inventors:
-
- Berkeley, CA
- Castro Valley, CA
- Oakland, CA
- Livermore, CA
- Issue Date:
- Research Org.:
- Sandia National Laboratories (SNL), Albuquerque, NM, and Livermore, CA (United States)
- OSTI Identifier:
- 874635
- Patent Number(s):
- 6428666
- Assignee:
- Sandia National Laboratories (Livermore, CA)
- Patent Classifications (CPCs):
-
G - PHYSICS G01 - MEASURING G01N - INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
B - PERFORMING OPERATIONS B01 - PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL B01J - CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY
- DOE Contract Number:
- AC04-94AL85000
- Resource Type:
- Patent
- Country of Publication:
- United States
- Language:
- English
- Subject:
- electrokinetic; concentration; charged; molecules; method; separating; concentrating; species; uncharged; neutral; regardless; size; differential; reversible; electric; field; induced; retention; molecular; aggregates; dimers; polymers; multimers; colloids; micelles; liposomes; volumes; surfaces; porous; materials; retained; subsequently; quantitatively; removed; material; pressure; driven; flow; passes; volume; independent; direction; multi-directional; required; pass; unimpeded; effecting; complete; separation; factors; 1000-fold; electric field; flow field; charged species; field induced; /204/210/
Citation Formats
Singh, Anup K, Neyer, David W, Schoeniger, Joseph S, and Garguilo, Michael G. Electrokinetic concentration of charged molecules. United States: N. p., 2002.
Web.
Singh, Anup K, Neyer, David W, Schoeniger, Joseph S, & Garguilo, Michael G. Electrokinetic concentration of charged molecules. United States.
Singh, Anup K, Neyer, David W, Schoeniger, Joseph S, and Garguilo, Michael G. Tue .
"Electrokinetic concentration of charged molecules". United States. https://www.osti.gov/servlets/purl/874635.
@article{osti_874635,
title = {Electrokinetic concentration of charged molecules},
author = {Singh, Anup K and Neyer, David W and Schoeniger, Joseph S and Garguilo, Michael G},
abstractNote = {A method for separating and concentrating charged species from uncharged or neutral species regardless of size differential. The method uses reversible electric field induced retention of charged species, that can include molecules and molecular aggregates such as dimers, polymers, multimers, colloids, micelles, and liposomes, in volumes and on surfaces of porous materials. The retained charged species are subsequently quantitatively removed from the porous material by a pressure driven flow that passes through the retention volume and is independent of direction thus, a multi-directional flow field is not required. Uncharged species pass through the system unimpeded thus effecting a complete separation of charged and uncharged species and making possible concentration factors greater than 1000-fold.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {2002},
month = {1}
}
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