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Title: Portable biochip scanner device

Abstract

A portable biochip scanner device used to detect and acquire fluorescence signal data from biological microchips (biochips) is provided. The portable biochip scanner device employs a laser for emitting an excitation beam. An optical fiber delivers the laser beam to a portable biochip scanner. A lens collimates the laser beam, the collimated laser beam is deflected by a dichroic mirror and focused by an objective lens onto a biochip. The fluorescence light from the biochip is collected and collimated by the objective lens. The fluorescence light is delivered to a photomultiplier tube (PMT) via an emission filter and a focusing lens. The focusing lens focuses the fluorescence light into a pinhole. A signal output of the PMT is processed and displayed.

Inventors:
 [1];  [2];  [3]
  1. (Troitsk, RU)
  2. (Moscow, RU)
  3. (Darien, IL)
Issue Date:
Research Org.:
Argonne National Laboratory (ANL), Argonne, IL
OSTI Identifier:
874525
Patent Number(s):
6407395
Assignee:
The University of Chicago (Chicago, IL) ANL
DOE Contract Number:  
W-31109-ENG-38
Resource Type:
Patent
Country of Publication:
United States
Language:
English
Subject:
portable; biochip; scanner; device; detect; acquire; fluorescence; signal; data; biological; microchips; biochips; provided; employs; laser; emitting; excitation; beam; optical; fiber; delivers; lens; collimates; collimated; deflected; dichroic; mirror; focused; objective; light; collected; delivered; photomultiplier; tube; pmt; via; emission; filter; focusing; focuses; pinhole; output; processed; displayed; laser beam; optical fiber; focusing lens; device employs; /250/

Citation Formats

Perov, Alexander, Sharonov, Alexei, and Mirzabekov, Andrei D. Portable biochip scanner device. United States: N. p., 2002. Web.
Perov, Alexander, Sharonov, Alexei, & Mirzabekov, Andrei D. Portable biochip scanner device. United States.
Perov, Alexander, Sharonov, Alexei, and Mirzabekov, Andrei D. Tue . "Portable biochip scanner device". United States. https://www.osti.gov/servlets/purl/874525.
@article{osti_874525,
title = {Portable biochip scanner device},
author = {Perov, Alexander and Sharonov, Alexei and Mirzabekov, Andrei D.},
abstractNote = {A portable biochip scanner device used to detect and acquire fluorescence signal data from biological microchips (biochips) is provided. The portable biochip scanner device employs a laser for emitting an excitation beam. An optical fiber delivers the laser beam to a portable biochip scanner. A lens collimates the laser beam, the collimated laser beam is deflected by a dichroic mirror and focused by an objective lens onto a biochip. The fluorescence light from the biochip is collected and collimated by the objective lens. The fluorescence light is delivered to a photomultiplier tube (PMT) via an emission filter and a focusing lens. The focusing lens focuses the fluorescence light into a pinhole. A signal output of the PMT is processed and displayed.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {2002},
month = {1}
}

Patent:

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