Portable biochip scanner device
Abstract
A portable biochip scanner device used to detect and acquire fluorescence signal data from biological microchips (biochips) is provided. The portable biochip scanner device employs a laser for emitting an excitation beam. An optical fiber delivers the laser beam to a portable biochip scanner. A lens collimates the laser beam, the collimated laser beam is deflected by a dichroic mirror and focused by an objective lens onto a biochip. The fluorescence light from the biochip is collected and collimated by the objective lens. The fluorescence light is delivered to a photomultiplier tube (PMT) via an emission filter and a focusing lens. The focusing lens focuses the fluorescence light into a pinhole. A signal output of the PMT is processed and displayed.
- Inventors:
-
- Troitsk, RU
- Moscow, RU
- Darien, IL
- Issue Date:
- Research Org.:
- Argonne National Laboratory (ANL), Argonne, IL (United States)
- OSTI Identifier:
- 874525
- Patent Number(s):
- 6407395
- Assignee:
- The University of Chicago (Chicago, IL)
- Patent Classifications (CPCs):
-
B - PERFORMING OPERATIONS B01 - PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL B01J - CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY
G - PHYSICS G01 - MEASURING G01N - INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- DOE Contract Number:
- W-31109-ENG-38
- Resource Type:
- Patent
- Country of Publication:
- United States
- Language:
- English
- Subject:
- portable; biochip; scanner; device; detect; acquire; fluorescence; signal; data; biological; microchips; biochips; provided; employs; laser; emitting; excitation; beam; optical; fiber; delivers; lens; collimates; collimated; deflected; dichroic; mirror; focused; objective; light; collected; delivered; photomultiplier; tube; pmt; via; emission; filter; focusing; focuses; pinhole; output; processed; displayed; laser beam; optical fiber; focusing lens; device employs; /250/
Citation Formats
Perov, Alexander, Sharonov, Alexei, and Mirzabekov, Andrei D. Portable biochip scanner device. United States: N. p., 2002.
Web.
Perov, Alexander, Sharonov, Alexei, & Mirzabekov, Andrei D. Portable biochip scanner device. United States.
Perov, Alexander, Sharonov, Alexei, and Mirzabekov, Andrei D. Tue .
"Portable biochip scanner device". United States. https://www.osti.gov/servlets/purl/874525.
@article{osti_874525,
title = {Portable biochip scanner device},
author = {Perov, Alexander and Sharonov, Alexei and Mirzabekov, Andrei D},
abstractNote = {A portable biochip scanner device used to detect and acquire fluorescence signal data from biological microchips (biochips) is provided. The portable biochip scanner device employs a laser for emitting an excitation beam. An optical fiber delivers the laser beam to a portable biochip scanner. A lens collimates the laser beam, the collimated laser beam is deflected by a dichroic mirror and focused by an objective lens onto a biochip. The fluorescence light from the biochip is collected and collimated by the objective lens. The fluorescence light is delivered to a photomultiplier tube (PMT) via an emission filter and a focusing lens. The focusing lens focuses the fluorescence light into a pinhole. A signal output of the PMT is processed and displayed.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {2002},
month = {1}
}
Works referenced in this record:
DNA analysis and diagnostics on oligonucleotide microchips.
journal, May 1996
- Yershov, G.; Barsky, V.; Belgovskiy, A.
- Proceedings of the National Academy of Sciences, Vol. 93, Issue 10