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Title: Polymeric assay film for direct colorimetric detection

Abstract

A lipid bilayer with affinity to an analyte, which directly signals binding by a changes in the light absorption spectra. This novel assay means and method has special applications in the drug development and medical testing fields. Using a spectrometer, the system is easily automated, and a multiple well embodiment allows inexpensive screening and sequential testing. This invention also has applications in industry for feedstock and effluent monitoring.

Inventors:
 [1];  [2];  [1]
  1. Albany, CA
  2. Bozeman, MT
Issue Date:
Research Org.:
Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States)
OSTI Identifier:
874464
Patent Number(s):
6395561
Assignee:
Regents of the University of California (Oakland, CA)
Patent Classifications (CPCs):
B - PERFORMING OPERATIONS B82 - NANOTECHNOLOGY B82Y - SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES
G - PHYSICS G01 - MEASURING G01N - INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
DOE Contract Number:  
AC03-76SF00098
Resource Type:
Patent
Country of Publication:
United States
Language:
English
Subject:
polymeric; assay; film; direct; colorimetric; detection; lipid; bilayer; affinity; analyte; directly; signals; binding; changes; light; absorption; spectra; novel; means; method; special; applications; drug; medical; testing; fields; spectrometer; easily; automated; multiple; embodiment; allows; inexpensive; screening; sequential; industry; feedstock; effluent; monitoring; light absorption; absorption spectra; special application; /436/435/

Citation Formats

Charych, Deborah, Nagy, Jon, and Spevak, Wayne. Polymeric assay film for direct colorimetric detection. United States: N. p., 2002. Web.
Charych, Deborah, Nagy, Jon, & Spevak, Wayne. Polymeric assay film for direct colorimetric detection. United States.
Charych, Deborah, Nagy, Jon, and Spevak, Wayne. Tue . "Polymeric assay film for direct colorimetric detection". United States. https://www.osti.gov/servlets/purl/874464.
@article{osti_874464,
title = {Polymeric assay film for direct colorimetric detection},
author = {Charych, Deborah and Nagy, Jon and Spevak, Wayne},
abstractNote = {A lipid bilayer with affinity to an analyte, which directly signals binding by a changes in the light absorption spectra. This novel assay means and method has special applications in the drug development and medical testing fields. Using a spectrometer, the system is easily automated, and a multiple well embodiment allows inexpensive screening and sequential testing. This invention also has applications in industry for feedstock and effluent monitoring.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {2002},
month = {1}
}

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