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Title: Integrated multiplexed capillary electrophoresis system

Abstract

The present invention provides an integrated multiplexed capillary electrophoresis system for the analysis of sample analytes. The system integrates and automates multiple components, such as chromatographic columns and separation capillaries, and further provides a detector for the detection of analytes eluting from the separation capillaries. The system employs multiplexed freeze/thaw valves to manage fluid flow and sample movement. The system is computer controlled and is capable of processing samples through reaction, purification, denaturation, pre-concentration, injection, separation and detection in parallel fashion. Methods employing the system of the invention are also provided.

Inventors:
 [1];  [1]
  1. (Ames, IA)
Issue Date:
Research Org.:
Ames Laboratory (AMES), Ames, IA; Iowa State University, Ames, IA (US)
OSTI Identifier:
874423
Patent Number(s):
6387234
Application Number:
09/144,170
Assignee:
Iowa State University Research Foundation, Inc. (Ames, IA) AMES
DOE Contract Number:  
W-7405-ENG-82
Resource Type:
Patent
Country of Publication:
United States
Language:
English
Subject:
integrated; multiplexed; capillary; electrophoresis; provides; analysis; sample; analytes; integrates; automates; multiple; components; chromatographic; columns; separation; capillaries; detector; detection; eluting; employs; freezethaw; valves; manage; fluid; flow; movement; computer; controlled; capable; processing; samples; reaction; purification; denaturation; pre-concentration; injection; parallel; fashion; methods; employing; provided; fluid flow; computer control; /204/422/

Citation Formats

Yeung, Edward S., and Tan, Hongdong. Integrated multiplexed capillary electrophoresis system. United States: N. p., 2002. Web.
Yeung, Edward S., & Tan, Hongdong. Integrated multiplexed capillary electrophoresis system. United States.
Yeung, Edward S., and Tan, Hongdong. Tue . "Integrated multiplexed capillary electrophoresis system". United States. https://www.osti.gov/servlets/purl/874423.
@article{osti_874423,
title = {Integrated multiplexed capillary electrophoresis system},
author = {Yeung, Edward S. and Tan, Hongdong},
abstractNote = {The present invention provides an integrated multiplexed capillary electrophoresis system for the analysis of sample analytes. The system integrates and automates multiple components, such as chromatographic columns and separation capillaries, and further provides a detector for the detection of analytes eluting from the separation capillaries. The system employs multiplexed freeze/thaw valves to manage fluid flow and sample movement. The system is computer controlled and is capable of processing samples through reaction, purification, denaturation, pre-concentration, injection, separation and detection in parallel fashion. Methods employing the system of the invention are also provided.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {2002},
month = {5}
}

Patent:

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