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Title: Method for analyzing nucleic acids by means of a substrate having a microchannel structure containing immobilized nucleic acid probes

Abstract

A method and apparatus for analyzing nucleic acids includes immobilizing nucleic probes at specific sites within a microchannel structure and moving target nucleic acids into proximity to the probes in order to allow hybridization and fluorescence detection of specific target sequences.

Inventors:
 [1];  [2]
  1. (Knoxville, TN)
  2. (Oak Ridge, TN)
Issue Date:
Research Org.:
LOCKHEED MARTIN ENRGY SYST INC
OSTI Identifier:
874367
Patent Number(s):
6376181
Assignee:
UT-Battelle, LLC (Oak Ridge, TN) ORNL
DOE Contract Number:  
AC05-84OR21400
Resource Type:
Patent
Country of Publication:
United States
Language:
English
Subject:
method; analyzing; nucleic; acids; means; substrate; microchannel; structure; containing; immobilized; acid; probes; apparatus; immobilizing; specific; sites; moving; target; proximity; allow; hybridization; fluorescence; detection; sequences; nucleic acid; target nucleic; acid probe; channel structure; /435/436/

Citation Formats

Ramsey, J. Michael, and Foote, Robert S. Method for analyzing nucleic acids by means of a substrate having a microchannel structure containing immobilized nucleic acid probes. United States: N. p., 2002. Web.
Ramsey, J. Michael, & Foote, Robert S. Method for analyzing nucleic acids by means of a substrate having a microchannel structure containing immobilized nucleic acid probes. United States.
Ramsey, J. Michael, and Foote, Robert S. Tue . "Method for analyzing nucleic acids by means of a substrate having a microchannel structure containing immobilized nucleic acid probes". United States. https://www.osti.gov/servlets/purl/874367.
@article{osti_874367,
title = {Method for analyzing nucleic acids by means of a substrate having a microchannel structure containing immobilized nucleic acid probes},
author = {Ramsey, J. Michael and Foote, Robert S.},
abstractNote = {A method and apparatus for analyzing nucleic acids includes immobilizing nucleic probes at specific sites within a microchannel structure and moving target nucleic acids into proximity to the probes in order to allow hybridization and fluorescence detection of specific target sequences.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {2002},
month = {1}
}

Patent:

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