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Title: Microfabricated capillary electrophoresis chip and method for simultaneously detecting multiple redox labels

Abstract

This invention relates to a microfabricated capillary electrophoresis chip for detecting multiple redox-active labels simultaneously using a matrix coding scheme and to a method of selectively labeling analytes for simultaneous electrochemical detection of multiple label-analyte conjugates after electrophoretic or chromatographic separation.

Inventors:
 [1];  [2];  [3];  [4]
  1. Moraga, CA
  2. Berkeley, CA
  3. Walnut Creek, CA
  4. Orinda, CA
Issue Date:
Research Org.:
Univ. of California (United States)
OSTI Identifier:
874303
Patent Number(s):
6361671
Assignee:
The Regents of the University of California (Oakland, CA)
Patent Classifications (CPCs):
G - PHYSICS G01 - MEASURING G01N - INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
DOE Contract Number:  
FG03-91ER61125
Resource Type:
Patent
Country of Publication:
United States
Language:
English
Subject:
microfabricated; capillary; electrophoresis; chip; method; simultaneously; detecting; multiple; redox; labels; relates; redox-active; matrix; coding; scheme; selectively; labeling; analytes; simultaneous; electrochemical; detection; label-analyte; conjugates; electrophoretic; chromatographic; separation; capillary electrophoresis; /204/210/422/

Citation Formats

Mathies, Richard A, Singhal, Pankaj, Xie, Jin, and Glazer, Alexander N. Microfabricated capillary electrophoresis chip and method for simultaneously detecting multiple redox labels. United States: N. p., 2002. Web.
Mathies, Richard A, Singhal, Pankaj, Xie, Jin, & Glazer, Alexander N. Microfabricated capillary electrophoresis chip and method for simultaneously detecting multiple redox labels. United States.
Mathies, Richard A, Singhal, Pankaj, Xie, Jin, and Glazer, Alexander N. Tue . "Microfabricated capillary electrophoresis chip and method for simultaneously detecting multiple redox labels". United States. https://www.osti.gov/servlets/purl/874303.
@article{osti_874303,
title = {Microfabricated capillary electrophoresis chip and method for simultaneously detecting multiple redox labels},
author = {Mathies, Richard A and Singhal, Pankaj and Xie, Jin and Glazer, Alexander N},
abstractNote = {This invention relates to a microfabricated capillary electrophoresis chip for detecting multiple redox-active labels simultaneously using a matrix coding scheme and to a method of selectively labeling analytes for simultaneous electrochemical detection of multiple label-analyte conjugates after electrophoretic or chromatographic separation.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {Tue Jan 01 00:00:00 EST 2002},
month = {Tue Jan 01 00:00:00 EST 2002}
}

Works referenced in this record:

Direct Electrochemical Detection of Purine- and Pyrimidine-Based Nucleotides with Sinusoidal Voltammetry
journal, September 1997


Electrochemical detectors ? tailormade techniques for liquid chromatography and capillary electrophoresis?
journal, March 1996


Capillary electrophoresis with NDA derivatization and electrochemical detection for the analysis of cellular amino acids
journal, January 1998