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Title: Oncoprotein protein kinase

Abstract

The present invention provides an isolated polynucleotide encoding a c-Jun peptide consisting of about amino acid residues 33 to 79 as set fort in SEQ ID NO: 10 or conservative variations thereof. The invention also provides a method for producing a peptide of SEQ ID NO:1 comprising (a) culturing a host cell containing a polynucleotide encoding a c-Jun peptide consisting of about amino acid residues 33 to 79 as set forth in SEQ ID NO: 10 under conditions which allow expression of the polynucleotide; and (b) obtaining the peptide of SEQ ID NO:1.

Inventors:
 [1];  [1];  [2]
  1. San Diego, CA
  2. La Jolla, CA
Issue Date:
Research Org.:
Univ. of California (United States)
OSTI Identifier:
874218
Patent Number(s):
6342595
Application Number:
09/461649
Assignee:
The Regents of the University of California (Oakland, CA)
Patent Classifications (CPCs):
C - CHEMISTRY C07 - ORGANIC CHEMISTRY C07K - PEPTIDES
Y - NEW / CROSS SECTIONAL TECHNOLOGIES Y10 - TECHNICAL SUBJECTS COVERED BY FORMER USPC Y10S - TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
DOE Contract Number:  
FG03-86ER60429
Resource Type:
Patent
Country of Publication:
United States
Language:
English
Subject:
oncoprotein; protein; kinase; provides; isolated; polynucleotide; encoding; c-jun; peptide; consisting; amino; acid; residues; 33; 79; set; fort; seq; 10; conservative; variations; method; producing; no1; comprising; culturing; host; cell; containing; forth; conditions; allow; expression; obtaining; amino acid; set forth; protein kinase; oncoprotein protein; acid residue; /999/435/

Citation Formats

Karin, Michael, Hibi, Masahiko, and Lin, Anning. Oncoprotein protein kinase. United States: N. p., 2002. Web.
Karin, Michael, Hibi, Masahiko, & Lin, Anning. Oncoprotein protein kinase. United States.
Karin, Michael, Hibi, Masahiko, and Lin, Anning. Tue . "Oncoprotein protein kinase". United States. https://www.osti.gov/servlets/purl/874218.
@article{osti_874218,
title = {Oncoprotein protein kinase},
author = {Karin, Michael and Hibi, Masahiko and Lin, Anning},
abstractNote = {The present invention provides an isolated polynucleotide encoding a c-Jun peptide consisting of about amino acid residues 33 to 79 as set fort in SEQ ID NO: 10 or conservative variations thereof. The invention also provides a method for producing a peptide of SEQ ID NO:1 comprising (a) culturing a host cell containing a polynucleotide encoding a c-Jun peptide consisting of about amino acid residues 33 to 79 as set forth in SEQ ID NO: 10 under conditions which allow expression of the polynucleotide; and (b) obtaining the peptide of SEQ ID NO:1.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {2002},
month = {1}
}

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Works referenced in this record:

An insulin-stimulated protein kinase similar to yeast kinases involved in cell cycle control
journal, July 1990


Requirement for integration of signals from two distinct phosphorylation pathways for activation of MAP kinase
journal, February 1990


Phorbol esters stimulate the phosphorylation of c-Jun but not v-Jun: regulation by the N-terminal delta domain.
journal, June 1992


Parallel signal processing among mammalian MAPKs
journal, March 1995


Phosphorylation of c-jun mediated by MAP kinases
journal, October 1991