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Title: Plant fatty acid hydroxylases

Abstract

This invention relates to plant fatty acyl hydroxylases. Methods to use conserved amino acid or nucleotide sequences to obtain plant fatty acyl hydroxylases are described. Also described is the use of cDNA clones encoding a plant hydroxylase to produce a family of hydroxylated fatty acids in transgenic plants. In addition, the use of genes encoding fatty acid hydroxylases or desaturases to alter the level of lipid fatty acid unsaturation in transgenic plants is described.

Inventors:
 [1];  [2];  [3]
  1. Portola Valley, CA
  2. Burlingame, CA
  3. Lexington, KY
Issue Date:
Research Org.:
Carnegie Institute of Washington (US)
OSTI Identifier:
874093
Patent Number(s):
6310194
Assignee:
Carnegie Institution of Washington (Washington, DC); Monsanto Company, Ltd. (St. Louis, MO)
Patent Classifications (CPCs):
C - CHEMISTRY C12 - BIOCHEMISTRY C12N - MICROORGANISMS OR ENZYMES
DOE Contract Number:  
FG02-94ER20133
Resource Type:
Patent
Country of Publication:
United States
Language:
English
Subject:
plant; fatty; acid; hydroxylases; relates; acyl; methods; conserved; amino; nucleotide; sequences; obtain; described; cdna; clones; encoding; hydroxylase; produce; family; hydroxylated; acids; transgenic; plants; addition; genes; desaturases; alter; level; lipid; unsaturation; amino acid; nucleotide sequence; cdna clone; plant fatty; fatty acyl; /999/800/

Citation Formats

Somerville, Chris, Broun, Pierre, and van de Loo, Frank. Plant fatty acid hydroxylases. United States: N. p., 2001. Web.
Somerville, Chris, Broun, Pierre, & van de Loo, Frank. Plant fatty acid hydroxylases. United States.
Somerville, Chris, Broun, Pierre, and van de Loo, Frank. Mon . "Plant fatty acid hydroxylases". United States. https://www.osti.gov/servlets/purl/874093.
@article{osti_874093,
title = {Plant fatty acid hydroxylases},
author = {Somerville, Chris and Broun, Pierre and van de Loo, Frank},
abstractNote = {This invention relates to plant fatty acyl hydroxylases. Methods to use conserved amino acid or nucleotide sequences to obtain plant fatty acyl hydroxylases are described. Also described is the use of cDNA clones encoding a plant hydroxylase to produce a family of hydroxylated fatty acids in transgenic plants. In addition, the use of genes encoding fatty acid hydroxylases or desaturases to alter the level of lipid fatty acid unsaturation in transgenic plants is described.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {Mon Jan 01 00:00:00 EST 2001},
month = {Mon Jan 01 00:00:00 EST 2001}
}

Works referenced in this record:

Expression of the ?-subunit of ?-conglycinin in seeds of transgenic plants
journal, November 1987


Basic local alignment search tool
journal, October 1990


Construction and sequence of cDNA for rat liver stearyl coenzyme A desaturase.
journal, October 1986


The role of cytochrome b5 in Δ12 desaturation of oleic acid by microsomes of safflower (Carthamus tinctorius L.)
journal, February 1991


Plasmid [omega]-3 Fatty Acid Desaturase cDNA from Ricinus communis
journal, May 1994


Recent Studies of the Enzymic Synthesis of Ricinoleic Acid by Developing Castor Beans
journal, April 1981


Arabidopsis FAD2 gene encodes the enzyme that is essential for polyunsaturated lipid synthesis.
journal, January 1994


Broad host range DNA cloning system for gram-negative bacteria: construction of a gene bank of Rhizobium meliloti.
journal, December 1980


Seed development in Ricinus communis (castor bean). I. Descriptive morphology
journal, September 1982


Analysis of oil and meal from Lesquerella fendleri seed
journal, July 1990


Glycerolipid Synthesis: Biochemistry and Regulation
journal, June 1991


Phospholipids of palash ( Butea monosperma ), papaya ( Carica papaya ), jangli badam ( Sterculia foetida ), coriander ( Coriandrum sativum ) and carrot ( Daucus carota ) seeds
journal, October 1987


Characterization of two divergent β-tubulin genes from Colletotrichum graminicola
journal, February 1990


Effective vectors for transformation, expression of heterologous genes, and assaying transposon excision in transgenic plants
journal, November 1992


Modification of Plant Lipid Synthesis
journal, May 1995


A bifunctional oleate 12‐hydroxylase: desaturase from Lesquerella fendleri
journal, January 1998


Octopine Ti-plasmid deletion mutants of Agrobacterium tumefaciens with emphasis on the right side of the T-region
journal, January 1982


Signal sequences
journal, July 1985


[19] Isolation of multigene families and determination of homologies by filter hybridization methods
book, January 1983


Formation of oil in the seed of Ricinus Communis l.
journal, September 1963


The Biosynthesis of Ricinoleic acid
journal, May 1965


Rapid isolation of high molecular weight plant DNA
journal, January 1980


The mechanism of ricinoleic acid biosynthesis in Ricinuscommunis seeds
journal, November 1967


Occurrence of ricinoleic acid in submerged cultures of variousClaviceps sp.
journal, November 1985


Cloning of Higher Plant [omega]-3 Fatty Acid Desaturases
journal, October 1993


A Comparison of the Metabolic Fate of Fatty Acids of Different Chain Lengths in Developing Oilseeds
journal, July 1989


The Biosynthesis of Ricinoleic Acid by Claviceps purpurea
journal, September 1966


The Pseudomonas oleovorans alkane hydroxylase gene
journal, April 1989


Mechanisms and stereochemistry in fatty acid metabolism
journal, August 1970


DST sequences, highly conserved among plant SAUR genes, target reporter transcripts for rapid decay in tobacco.
journal, June 1993


Primary structure of xylene monooxygenase: similarities to and differences from the alkane hydroxylation system.
journal, January 1991


Map-based cloning of a gene controlling omega-3 fatty acid desaturation in Arabidopsis
journal, November 1992


How and Why Do Plants Inactivate Homologous (Trans)genes?
journal, March 1995


Fat Metabolism in Higher Plants
journal, December 1966


Catalytic Plasticity of Fatty Acid Modification Enzymes Underlying Chemical Diversity of Plant Lipids
journal, November 1998


An oleate 12-hydroxylase from Ricinus communis L. is a fatty acyl desaturase homolog.
journal, July 1995