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Title: High throughput analysis of samples in flowing liquid

Abstract

Apparatus and method enable imaging multiple fluorescent sample particles in a single flow channel. A flow channel defines a flow direction for samples in a flow stream and has a viewing plane perpendicular to the flow direction. A laser beam is formed as a ribbon having a width effective to cover the viewing plane. Imaging optics are arranged to view the viewing plane to form an image of the fluorescent sample particles in the flow stream, and a camera records the image formed by the imaging optics.

Inventors:
 [1];  [1];  [1];  [1];  [2];  [3]
  1. Los Alamos, NM
  2. Fort Collins, CO
  3. White Rock, NM
Issue Date:
Research Org.:
Los Alamos National Laboratory (LANL), Los Alamos, NM
OSTI Identifier:
874091
Patent Number(s):
6309886
Assignee:
The Regents of the University of California (Los Alamos, NM)
DOE Contract Number:  
W-7405-ENG-36
Resource Type:
Patent
Country of Publication:
United States
Language:
English
Subject:
throughput; analysis; samples; flowing; liquid; apparatus; method; enable; imaging; multiple; fluorescent; sample; particles; single; flow; channel; defines; direction; stream; viewing; plane; perpendicular; laser; beam; formed; ribbon; width; effective; cover; optics; arranged; view; form; image; camera; records; laser beam; flow stream; flowing liquid; /436/356/422/

Citation Formats

Ambrose, W Patrick, Grace, W Kevin, Goodwin, Peter M, Jett, James H, Orden, Alan Van, and Keller, Richard A. High throughput analysis of samples in flowing liquid. United States: N. p., 2001. Web.
Ambrose, W Patrick, Grace, W Kevin, Goodwin, Peter M, Jett, James H, Orden, Alan Van, & Keller, Richard A. High throughput analysis of samples in flowing liquid. United States.
Ambrose, W Patrick, Grace, W Kevin, Goodwin, Peter M, Jett, James H, Orden, Alan Van, and Keller, Richard A. Mon . "High throughput analysis of samples in flowing liquid". United States. https://www.osti.gov/servlets/purl/874091.
@article{osti_874091,
title = {High throughput analysis of samples in flowing liquid},
author = {Ambrose, W Patrick and Grace, W Kevin and Goodwin, Peter M and Jett, James H and Orden, Alan Van and Keller, Richard A},
abstractNote = {Apparatus and method enable imaging multiple fluorescent sample particles in a single flow channel. A flow channel defines a flow direction for samples in a flow stream and has a viewing plane perpendicular to the flow direction. A laser beam is formed as a ribbon having a width effective to cover the viewing plane. Imaging optics are arranged to view the viewing plane to form an image of the fluorescent sample particles in the flow stream, and a camera records the image formed by the imaging optics.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {2001},
month = {1}
}

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