Nucleic acid-coupled colorimetric analyte detectors
Abstract
The present invention relates to methods and compositions for the direct detection of analytes and membrane conformational changes through the detection of color changes in biopolymeric materials. In particular, the present invention provide for the direct colorimetric detection of analytes using nucleic acid ligands at surfaces of polydiacetylene liposomes and related molecular layer systems.
- Inventors:
-
- Albany, CA
- Mainz, DE
- Issue Date:
- Research Org.:
- Lawrence Berkeley National Laboratory (LBNL), Berkeley, CA (United States)
- OSTI Identifier:
- 874071
- Patent Number(s):
- 6306598
- Assignee:
- Regents of the University of California (Oakland, CA)
- Patent Classifications (CPCs):
-
A - HUMAN NECESSITIES A61 - MEDICAL OR VETERINARY SCIENCE A61K - PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
B - PERFORMING OPERATIONS B82 - NANOTECHNOLOGY B82Y - SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES
- DOE Contract Number:
- AC03-76SF00098
- Resource Type:
- Patent
- Country of Publication:
- United States
- Language:
- English
- Subject:
- nucleic; acid-coupled; colorimetric; analyte; detectors; relates; methods; compositions; direct; detection; analytes; membrane; conformational; changes; color; biopolymeric; materials; provide; acid; ligands; surfaces; polydiacetylene; liposomes; related; molecular; layer; systems; nucleic acid; polymeric material; color change; direct detection; analyte detector; /435/422/436/999/
Citation Formats
Charych, Deborah H, and Jonas, Ulrich. Nucleic acid-coupled colorimetric analyte detectors. United States: N. p., 2001.
Web.
Charych, Deborah H, & Jonas, Ulrich. Nucleic acid-coupled colorimetric analyte detectors. United States.
Charych, Deborah H, and Jonas, Ulrich. Mon .
"Nucleic acid-coupled colorimetric analyte detectors". United States. https://www.osti.gov/servlets/purl/874071.
@article{osti_874071,
title = {Nucleic acid-coupled colorimetric analyte detectors},
author = {Charych, Deborah H and Jonas, Ulrich},
abstractNote = {The present invention relates to methods and compositions for the direct detection of analytes and membrane conformational changes through the detection of color changes in biopolymeric materials. In particular, the present invention provide for the direct colorimetric detection of analytes using nucleic acid ligands at surfaces of polydiacetylene liposomes and related molecular layer systems.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {2001},
month = {1}
}
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