Electrochemical methods for generation of a biological proton motive force and pyridine nucleotide cofactor regeneration
Abstract
Disclosed are methods using neutral red to mediate the interconversion of chemical and electrical energy. Electrically reduced neutral red has been found to promote cell growth and formation of reduced products by reversibly increasing the ratio of the reduced:oxidized forms of NAD(H) or NADP(H). Electrically reduced neutral red is able to serve as the sole source of reducing power for microbial cell growth. Neutral red is also able to promote conversion of chemical energy to electrical energy by facilitating the transfer of electrons from microbial reducing power to a fuel cell cathode.
- Inventors:
-
- Okemas, MI
- Seoul, KR
- Issue Date:
- Research Org.:
- Michigan State University (East Lansing, MI)
- OSTI Identifier:
- 873909
- Patent Number(s):
- 6270649
- Assignee:
- Michigan State University (East Lansing, MI)
- Patent Classifications (CPCs):
-
C - CHEMISTRY C12 - BIOCHEMISTRY C12N - MICROORGANISMS OR ENZYMES
C - CHEMISTRY C12 - BIOCHEMISTRY C12Q - MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS
- DOE Contract Number:
- FG02-93ER20108
- Resource Type:
- Patent
- Country of Publication:
- United States
- Language:
- English
- Subject:
- electrochemical; methods; generation; biological; proton; motive; force; pyridine; nucleotide; cofactor; regeneration; disclosed; neutral; mediate; interconversion; chemical; electrical; energy; electrically; reduced; found; promote; cell; growth; formation; products; reversibly; increasing; ratio; oxidized; forms; nad; nadp; serve; sole; source; reducing; power; microbial; conversion; facilitating; transfer; electrons; fuel; cathode; cell growth; fuel cell; chemical energy; electrical energy; electrochemical method; sole source; cell cathode; motive force; microbial cell; chemical method; oxidized form; /205/
Citation Formats
Zeikus, Joseph G, and Park, Doo. Electrochemical methods for generation of a biological proton motive force and pyridine nucleotide cofactor regeneration. United States: N. p., 2001.
Web.
Zeikus, Joseph G, & Park, Doo. Electrochemical methods for generation of a biological proton motive force and pyridine nucleotide cofactor regeneration. United States.
Zeikus, Joseph G, and Park, Doo. Mon .
"Electrochemical methods for generation of a biological proton motive force and pyridine nucleotide cofactor regeneration". United States. https://www.osti.gov/servlets/purl/873909.
@article{osti_873909,
title = {Electrochemical methods for generation of a biological proton motive force and pyridine nucleotide cofactor regeneration},
author = {Zeikus, Joseph G and Park, Doo},
abstractNote = {Disclosed are methods using neutral red to mediate the interconversion of chemical and electrical energy. Electrically reduced neutral red has been found to promote cell growth and formation of reduced products by reversibly increasing the ratio of the reduced:oxidized forms of NAD(H) or NADP(H). Electrically reduced neutral red is able to serve as the sole source of reducing power for microbial cell growth. Neutral red is also able to promote conversion of chemical energy to electrical energy by facilitating the transfer of electrons from microbial reducing power to a fuel cell cathode.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {Mon Jan 01 00:00:00 EST 2001},
month = {Mon Jan 01 00:00:00 EST 2001}
}
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