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Title: Production of amino acids using auxotrophic mutants of methylotrophic bacillus

Abstract

A method of producing amino acids by culturing an amino acid auxotroph of a biologically pure strain of a type I methylotrophic bacterium of the genus Bacillus which exhibits sustained growth at 50.degree. C. using methanol as a carbon and energy source and requiring vitamin B.sub.12 and biotin is provided.

Inventors:
 [1];  [2];  [3];  [4]
  1. Wayzata, MN
  2. St. Paul, MN
  3. Falcon Heights, MN
  4. Waconia, MN
Issue Date:
Research Org.:
Univ. of Minnesota, Minneapolis, MN (United States)
OSTI Identifier:
873858
Patent Number(s):
6261825
Application Number:
07/673,264
Assignee:
Regents of University of Minnesota (Minneapolis, MN)
Patent Classifications (CPCs):
C - CHEMISTRY C12 - BIOCHEMISTRY C12P - FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE {
C - CHEMISTRY C12 - BIOCHEMISTRY C12R - PROCESSES USING MICROORGANISMS
DOE Contract Number:  
AC02-82ER12029
Resource Type:
Patent
Country of Publication:
United States
Language:
English
Subject:
production; amino; acids; auxotrophic; mutants; methylotrophic; bacillus; method; producing; culturing; acid; auxotroph; biologically; pure; strain; type; bacterium; genus; exhibits; sustained; growth; 50; degree; methanol; carbon; energy; source; requiring; vitamin; 12; biotin; provided; biologically pure; amino acid; energy source; amino acids; methylotrophic bacillus; /435/

Citation Formats

Hanson, Richard S, Flickinger, Michael C, Schendel, Frederick J, and Guettler, Michael V. Production of amino acids using auxotrophic mutants of methylotrophic bacillus. United States: N. p., 2001. Web.
Hanson, Richard S, Flickinger, Michael C, Schendel, Frederick J, & Guettler, Michael V. Production of amino acids using auxotrophic mutants of methylotrophic bacillus. United States.
Hanson, Richard S, Flickinger, Michael C, Schendel, Frederick J, and Guettler, Michael V. Tue . "Production of amino acids using auxotrophic mutants of methylotrophic bacillus". United States. https://www.osti.gov/servlets/purl/873858.
@article{osti_873858,
title = {Production of amino acids using auxotrophic mutants of methylotrophic bacillus},
author = {Hanson, Richard S and Flickinger, Michael C and Schendel, Frederick J and Guettler, Michael V},
abstractNote = {A method of producing amino acids by culturing an amino acid auxotroph of a biologically pure strain of a type I methylotrophic bacterium of the genus Bacillus which exhibits sustained growth at 50.degree. C. using methanol as a carbon and energy source and requiring vitamin B.sub.12 and biotin is provided.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {2001},
month = {7}
}

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Works referenced in this record:

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The Prokaryotic Transposable Element Tn5
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L-lysine production at 50 degrees C by mutants of a newly isolated and characterized methylotrophic Bacillus sp.
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