skip to main content
DOE Patents title logo U.S. Department of Energy
Office of Scientific and Technical Information

Title: Composition for detection of cell density signal molecule

Abstract

Disclosed herein is a novel proteinaceous cell density signal molecule (CDS), which is secreted by fibroblastic cells in culture, preferably tendon cells, and which provides a means by which the cells self-regulate their proliferation and the expression of differentiated function. CDS, and the antibodies which recognize them, are important for the development of diagnostics and treatments for injuries and diseases involving connective tissues, particularly tendon. Also disclosed are methods of production and use.

Inventors:
 [1]
  1. (Oakland, CA)
Issue Date:
Research Org.:
Lawrence Berkeley National Laboratory (LBNL), Berkeley, CA
OSTI Identifier:
873781
Patent Number(s):
6245899
Assignee:
Regents of University of California (Oakland, CA) LBNL
DOE Contract Number:  
AC03-76SF00098
Resource Type:
Patent
Country of Publication:
United States
Language:
English
Subject:
composition; detection; cell; density; signal; molecule; disclosed; novel; proteinaceous; cds; secreted; fibroblastic; cells; culture; preferably; tendon; provides; means; self-regulate; proliferation; expression; differentiated; function; antibodies; recognize; diagnostics; treatments; injuries; diseases; involving; connective; tissues; particularly; methods; production; cell density; signal molecule; density signal; proteinaceous cell; novel proteinaceous; tendon cells; tendon cell; /530/

Citation Formats

Schwarz, Richard I. Composition for detection of cell density signal molecule. United States: N. p., 2001. Web.
Schwarz, Richard I. Composition for detection of cell density signal molecule. United States.
Schwarz, Richard I. Mon . "Composition for detection of cell density signal molecule". United States. https://www.osti.gov/servlets/purl/873781.
@article{osti_873781,
title = {Composition for detection of cell density signal molecule},
author = {Schwarz, Richard I.},
abstractNote = {Disclosed herein is a novel proteinaceous cell density signal molecule (CDS), which is secreted by fibroblastic cells in culture, preferably tendon cells, and which provides a means by which the cells self-regulate their proliferation and the expression of differentiated function. CDS, and the antibodies which recognize them, are important for the development of diagnostics and treatments for injuries and diseases involving connective tissues, particularly tendon. Also disclosed are methods of production and use.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {2001},
month = {1}
}

Patent:

Save / Share: