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Title: Baculovirus expression system and method for high throughput expression of genetic material

Abstract

The present invention provides novel recombinant baculovirus expression systems for expressing foreign genetic material in a host cell. Such expression systems are readily adapted to an automated method for expression foreign genetic material in a high throughput manner. In other aspects, the present invention features a novel automated method for determining the function of foreign genetic material by transfecting the same into a host by way of the recombinant baculovirus expression systems according to the present invention.

Inventors:
 [1];  [2]
  1. Benecia, CA
  2. Mill Valley, CA
Issue Date:
Research Org.:
Lawrence Livermore National Laboratory (LLNL), Livermore, CA (United States)
OSTI Identifier:
873700
Patent Number(s):
6225060
Assignee:
Onyx Pharmaceuticals, Inc. (Richmond, CA)
Patent Classifications (CPCs):
C - CHEMISTRY C07 - ORGANIC CHEMISTRY C07K - PEPTIDES
C - CHEMISTRY C12 - BIOCHEMISTRY C12N - MICROORGANISMS OR ENZYMES
DOE Contract Number:  
W-7405-ENG-48
Resource Type:
Patent
Country of Publication:
United States
Language:
English
Subject:
baculovirus; expression; method; throughput; genetic; material; provides; novel; recombinant; systems; expressing; foreign; host; cell; readily; adapted; automated; manner; aspects; features; determining; function; transfecting; according; expression systems; automated method; genetic material; provides novel; host cell; baculovirus expression; /435/999/

Citation Formats

Clark, Robin, and Davies, Anthony. Baculovirus expression system and method for high throughput expression of genetic material. United States: N. p., 2001. Web.
Clark, Robin, & Davies, Anthony. Baculovirus expression system and method for high throughput expression of genetic material. United States.
Clark, Robin, and Davies, Anthony. Mon . "Baculovirus expression system and method for high throughput expression of genetic material". United States. https://www.osti.gov/servlets/purl/873700.
@article{osti_873700,
title = {Baculovirus expression system and method for high throughput expression of genetic material},
author = {Clark, Robin and Davies, Anthony},
abstractNote = {The present invention provides novel recombinant baculovirus expression systems for expressing foreign genetic material in a host cell. Such expression systems are readily adapted to an automated method for expression foreign genetic material in a high throughput manner. In other aspects, the present invention features a novel automated method for determining the function of foreign genetic material by transfecting the same into a host by way of the recombinant baculovirus expression systems according to the present invention.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {Mon Jan 01 00:00:00 EST 2001},
month = {Mon Jan 01 00:00:00 EST 2001}
}

Works referenced in this record:

Functional High Level Expression of Cytochrome P450 CYP2D6 Using Baculoviral Expression Systems
journal, April 1996


Baculovirus systems for the expression of human gene products
journal, October 1993


Production and purification of novel secreted human proteins
journal, January 1997