Development of genetically engineered bacteria for production of selected aromatic compounds
Abstract
The cloning and expression of genes in the common aromatic pathway of E. coli are described. A compound for which chorismate, the final product of the common aromatic pathway, is an anabolic intermediate can be produced by cloning and expressing selected genes of the common aromatic pathway and the genes coding for enzymes necessary to convert chorismate to the selected compound. Plasmids carrying selected genes of the common aromatic pathway are also described.
- Inventors:
-
- Idaho Falls, ID
- Henderson, NV
- Scotia, NY
- Clifton Park, NY
- Issue Date:
- Research Org.:
- Idaho National Laboratory (INL), Idaho Falls, ID (United States)
- OSTI Identifier:
- 873644
- Patent Number(s):
- 6210937
- Assignee:
- Bechtel BWXT Idaho, LLC (Idaho Falls, ID)
- Patent Classifications (CPCs):
-
C - CHEMISTRY C12 - BIOCHEMISTRY C12N - MICROORGANISMS OR ENZYMES
C - CHEMISTRY C12 - BIOCHEMISTRY C12P - FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE {
- DOE Contract Number:
- AC07-94ID13223
- Resource Type:
- Patent
- Country of Publication:
- United States
- Language:
- English
- Subject:
- genetically; engineered; bacteria; production; selected; aromatic; compounds; cloning; expression; genes; common; pathway; coli; described; compound; chorismate; final; product; anabolic; intermediate; produced; expressing; coding; enzymes; convert; plasmids; carrying; aromatic compound; aromatic compounds; final product; genetically engineered; selected compound; genes coding; /435/
Citation Formats
Ward, Thomas E, Watkins, Carolyn S, Bulmer, Deborah K, Johnson, Bruce F, and Amaratunga, Mohan. Development of genetically engineered bacteria for production of selected aromatic compounds. United States: N. p., 2001.
Web.
Ward, Thomas E, Watkins, Carolyn S, Bulmer, Deborah K, Johnson, Bruce F, & Amaratunga, Mohan. Development of genetically engineered bacteria for production of selected aromatic compounds. United States.
Ward, Thomas E, Watkins, Carolyn S, Bulmer, Deborah K, Johnson, Bruce F, and Amaratunga, Mohan. Mon .
"Development of genetically engineered bacteria for production of selected aromatic compounds". United States. https://www.osti.gov/servlets/purl/873644.
@article{osti_873644,
title = {Development of genetically engineered bacteria for production of selected aromatic compounds},
author = {Ward, Thomas E and Watkins, Carolyn S and Bulmer, Deborah K and Johnson, Bruce F and Amaratunga, Mohan},
abstractNote = {The cloning and expression of genes in the common aromatic pathway of E. coli are described. A compound for which chorismate, the final product of the common aromatic pathway, is an anabolic intermediate can be produced by cloning and expressing selected genes of the common aromatic pathway and the genes coding for enzymes necessary to convert chorismate to the selected compound. Plasmids carrying selected genes of the common aromatic pathway are also described.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {Mon Jan 01 00:00:00 EST 2001},
month = {Mon Jan 01 00:00:00 EST 2001}
}
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Formation of 4-hydroxybenzoate in Escherichia coli: characterization of the ubiC gene and its encoded enzyme chorismate pyruvate-lyase
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- Siebert, M.; Severin, K.; Heide, L.
- Microbiology, Vol. 140, Issue 4