Implantable medical sensor system
Abstract
An implantable chemical sensor system for medical applications is described which permits selective recognition of an analyte using an expandable biocompatible sensor, such as a polymer, that undergoes a dimensional change in the presence of the analyte. The expandable polymer is incorporated into an electronic circuit component that changes its properties (e.g., frequency) when the polymer changes dimension. As the circuit changes its characteristics, an external interrogator transmits a signal transdermally to the transducer, and the concentration of the analyte is determined from the measured changes in the circuit. This invention may be used for minimally invasive monitoring of blood glucose levels in diabetic patients.
- Inventors:
-
- Pleasanton, CA
- (Modesto, CA)
- Oakland, CA
- Walnut Creek, CA
- Berkeley, CA
- Issue Date:
- Research Org.:
- Lawrence Livermore National Laboratory (LLNL), Livermore, CA (United States)
- OSTI Identifier:
- 873608
- Patent Number(s):
- 6201980
- Assignee:
- Regents of University of California (Oakland, CA)
- Patent Classifications (CPCs):
-
A - HUMAN NECESSITIES A61 - MEDICAL OR VETERINARY SCIENCE A61B - DIAGNOSIS
- DOE Contract Number:
- W-7405-ENG-48
- Resource Type:
- Patent
- Country of Publication:
- United States
- Language:
- English
- Subject:
- implantable; medical; sensor; chemical; applications; described; permits; selective; recognition; analyte; expandable; biocompatible; polymer; undergoes; dimensional; change; presence; incorporated; electronic; circuit; component; changes; properties; frequency; dimension; characteristics; external; interrogator; transmits; signal; transdermally; transducer; concentration; determined; measured; minimally; invasive; monitoring; blood; glucose; levels; diabetic; patients; blood glucose; circuit component; chemical sensor; electronic circuit; medical applications; permits selective; minimally invasive; dimensional change; medical sensor; /600/
Citation Formats
Darrow, Christopher B, Satcher, Jr., Joe H., Lane, Stephen M, Lee, Abraham P, and Wang, Amy W. Implantable medical sensor system. United States: N. p., 2001.
Web.
Darrow, Christopher B, Satcher, Jr., Joe H., Lane, Stephen M, Lee, Abraham P, & Wang, Amy W. Implantable medical sensor system. United States.
Darrow, Christopher B, Satcher, Jr., Joe H., Lane, Stephen M, Lee, Abraham P, and Wang, Amy W. Mon .
"Implantable medical sensor system". United States. https://www.osti.gov/servlets/purl/873608.
@article{osti_873608,
title = {Implantable medical sensor system},
author = {Darrow, Christopher B and Satcher, Jr., Joe H. and Lane, Stephen M and Lee, Abraham P and Wang, Amy W},
abstractNote = {An implantable chemical sensor system for medical applications is described which permits selective recognition of an analyte using an expandable biocompatible sensor, such as a polymer, that undergoes a dimensional change in the presence of the analyte. The expandable polymer is incorporated into an electronic circuit component that changes its properties (e.g., frequency) when the polymer changes dimension. As the circuit changes its characteristics, an external interrogator transmits a signal transdermally to the transducer, and the concentration of the analyte is determined from the measured changes in the circuit. This invention may be used for minimally invasive monitoring of blood glucose levels in diabetic patients.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {Mon Jan 01 00:00:00 EST 2001},
month = {Mon Jan 01 00:00:00 EST 2001}
}
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Works referenced in this record:
Data transmission from an implantable biotelemeter by load-shift keying using circuit configuration modulator
journal, May 1995
- Tang, Z.; Smith, B.; Schild, J. H.
- IEEE Transactions on Biomedical Engineering, Vol. 42, Issue 5
Glucose-Sensing Electrode Coated with Polymer Complex Gel Containing Phenylboronic Acid
journal, January 1996
- Kikuchi, Akihiko; Suzuki, Ken; Okabayashi, Osamu
- Analytical Chemistry, Vol. 68, Issue 5