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Title: NMR/MRI with hyperpolarized gas and high Tc SQUID

Abstract

A method and apparatus for the detection of nuclear magnetic resonance (NMR) signals and production of magnetic resonance imaging (MRI) from samples combines the use of hyperpolarized inert gases to enhance the NMR signals from target nuclei in a sample and a high critical temperature (Tc) superconducting quantum interference device (SQUID) to detect the NMR signals. The system operates in static magnetic fields of 3 mT or less (down to 0.1 mT), and at temperatures from liquid nitrogen (77K) to room temperature. Sample size is limited only by the size of the magnetic field coils and not by the detector. The detector is a high Tc SQUID magnetometer designed so that the SQUID detector can be very close to the sample, which can be at room temperature.

Inventors:
 [1];  [2];  [3];  [3];  [3]
  1. Eggenstein, DE
  2. Recife, BR
  3. Berkeley, CA
Issue Date:
Research Org.:
Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States)
OSTI Identifier:
873436
Patent Number(s):
6159444
Assignee:
Regents of University of California (Oakland, CA)
Patent Classifications (CPCs):
G - PHYSICS G01 - MEASURING G01R - MEASURING ELECTRIC VARIABLES
Y - NEW / CROSS SECTIONAL TECHNOLOGIES Y10 - TECHNICAL SUBJECTS COVERED BY FORMER USPC Y10T - TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
DOE Contract Number:  
AC03-76SF00098
Resource Type:
Patent
Country of Publication:
United States
Language:
English
Subject:
nmr; mri; hyperpolarized; gas; tc; squid; method; apparatus; detection; nuclear; magnetic; resonance; signals; production; imaging; samples; combines; inert; gases; enhance; target; nuclei; sample; critical; temperature; superconducting; quantum; interference; device; detect; operates; static; fields; mt; temperatures; liquid; nitrogen; 77k; size; limited; field; coils; detector; magnetometer; designed; close; resonance imaging; inert gases; field coils; quantum interference; magnetic resonance; critical temperature; magnetic field; magnetic fields; inert gas; nuclear magnetic; static magnetic; field coil; superconducting quantum; liquid nitrogen; interference device; target nuclei; /424/436/

Citation Formats

Schlenga, Klaus, de Souza, Ricardo E, Wong-Foy, Annjoe, Clarke, John, and Pines, Alexander. NMR/MRI with hyperpolarized gas and high Tc SQUID. United States: N. p., 2000. Web.
Schlenga, Klaus, de Souza, Ricardo E, Wong-Foy, Annjoe, Clarke, John, & Pines, Alexander. NMR/MRI with hyperpolarized gas and high Tc SQUID. United States.
Schlenga, Klaus, de Souza, Ricardo E, Wong-Foy, Annjoe, Clarke, John, and Pines, Alexander. Sat . "NMR/MRI with hyperpolarized gas and high Tc SQUID". United States. https://www.osti.gov/servlets/purl/873436.
@article{osti_873436,
title = {NMR/MRI with hyperpolarized gas and high Tc SQUID},
author = {Schlenga, Klaus and de Souza, Ricardo E and Wong-Foy, Annjoe and Clarke, John and Pines, Alexander},
abstractNote = {A method and apparatus for the detection of nuclear magnetic resonance (NMR) signals and production of magnetic resonance imaging (MRI) from samples combines the use of hyperpolarized inert gases to enhance the NMR signals from target nuclei in a sample and a high critical temperature (Tc) superconducting quantum interference device (SQUID) to detect the NMR signals. The system operates in static magnetic fields of 3 mT or less (down to 0.1 mT), and at temperatures from liquid nitrogen (77K) to room temperature. Sample size is limited only by the size of the magnetic field coils and not by the detector. The detector is a high Tc SQUID magnetometer designed so that the SQUID detector can be very close to the sample, which can be at room temperature.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {2000},
month = {1}
}

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