Extended length microchannels for high density high throughput electrophoresis systems
Abstract
High throughput electrophoresis systems which provide extended well-to-read distances on smaller substrates, thus compacting the overall systems. The electrophoresis systems utilize a high density array of microchannels for electrophoresis analysis with extended read lengths. The microchannel geometry can be used individually or in conjunction to increase the effective length of a separation channel while minimally impacting the packing density of channels. One embodiment uses sinusoidal microchannels, while another embodiment uses plural microchannels interconnected by a via. The extended channel systems can be applied to virtually any type of channel confined chromatography.
- Inventors:
-
- Livermore, CA
- Issue Date:
- Research Org.:
- Lawrence Livermore National Laboratory (LLNL), Livermore, CA (United States)
- OSTI Identifier:
- 873405
- Patent Number(s):
- 6153076
- Assignee:
- Regents of University of California (Oakland, CA)
- Patent Classifications (CPCs):
-
G - PHYSICS G01 - MEASURING G01N - INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- DOE Contract Number:
- W-7405-ENG-48
- Resource Type:
- Patent
- Country of Publication:
- United States
- Language:
- English
- Subject:
- extended; length; microchannels; density; throughput; electrophoresis; systems; provide; well-to-read; distances; substrates; compacting; overall; utilize; array; analysis; lengths; microchannel; geometry; individually; conjunction; increase; effective; separation; channel; minimally; impacting; packing; channels; embodiment; sinusoidal; plural; interconnected; via; applied; virtually; type; confined; chromatography; separation channel; packing density; provide extended; channel systems; electrophoresis systems; density array; throughput electrophoresis; extended length; /204/422/
Citation Formats
Davidson, James C, and Balch, Joseph W. Extended length microchannels for high density high throughput electrophoresis systems. United States: N. p., 2000.
Web.
Davidson, James C, & Balch, Joseph W. Extended length microchannels for high density high throughput electrophoresis systems. United States.
Davidson, James C, and Balch, Joseph W. Sat .
"Extended length microchannels for high density high throughput electrophoresis systems". United States. https://www.osti.gov/servlets/purl/873405.
@article{osti_873405,
title = {Extended length microchannels for high density high throughput electrophoresis systems},
author = {Davidson, James C and Balch, Joseph W},
abstractNote = {High throughput electrophoresis systems which provide extended well-to-read distances on smaller substrates, thus compacting the overall systems. The electrophoresis systems utilize a high density array of microchannels for electrophoresis analysis with extended read lengths. The microchannel geometry can be used individually or in conjunction to increase the effective length of a separation channel while minimally impacting the packing density of channels. One embodiment uses sinusoidal microchannels, while another embodiment uses plural microchannels interconnected by a via. The extended channel systems can be applied to virtually any type of channel confined chromatography.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {2000},
month = {1}
}
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Works referenced in this record:
Effects of Injection Schemes and Column Geometry on the Performance of Microchip Electrophoresis Devices
journal, April 1994
- Jacobson, Stephen C.; Hergenroder, Roland.; Koutny, Lance B.
- Analytical Chemistry, Vol. 66, Issue 7
Open Channel Electrochromatography on a Microchip
journal, July 1994
- Jacobson, Stephen C.; Hergenroeder, Roland.; Koutny, Lance B.
- Analytical Chemistry, Vol. 66, Issue 14