T-load microchannel array and fabrication method
Abstract
A three-dimensional (3-D) T-load for planar microchannel arrays for electrophoresis, for example, which enables sample injection directly onto a plane perpendicular to the microchannels' axis, at their ends. This is accomplished by forming input wells that extend beyond the ends of the microchannel thereby eliminating the right angle connection from the input well into the end of the microchannel. In addition, the T-load input well eases the placement of electrode in or adjacent the well and thus enables very efficient reproducible electrokinetic (ek) injection. The T-load input well eliminates the prior input well/microchannel alignment concerns, since the input well can be drilled after the top and bottom microchannel plates are bonded together. The T-load input well may extend partially or entirely through the bottom microchannel plate which enables more efficient gel and solution flushing, and also enables placement of multiple electrodes to assist in the ek sample injection.
- Inventors:
-
- Livermore, CA
- Issue Date:
- Research Org.:
- Lawrence Livermore National Laboratory (LLNL), Livermore, CA (United States)
- OSTI Identifier:
- 873190
- Patent Number(s):
- 6110332
- Assignee:
- Regents of University of California (Oakland, CA)
- Patent Classifications (CPCs):
-
G - PHYSICS G01 - MEASURING G01N - INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- DOE Contract Number:
- W-7405-ENG-48
- Resource Type:
- Patent
- Country of Publication:
- United States
- Language:
- English
- Subject:
- t-load; microchannel; array; fabrication; method; three-dimensional; 3-d; planar; arrays; electrophoresis; example; enables; sample; injection; directly; plane; perpendicular; microchannels; axis; accomplished; forming; input; extend; eliminating; angle; connection; addition; eases; placement; electrode; adjacent; efficient; reproducible; electrokinetic; ek; eliminates; prior; alignment; concerns; drilled; top; bottom; plates; bonded; partially; entirely; plate; solution; flushing; multiple; electrodes; assist; channel plate; multiple electrodes; fabrication method; plane perpendicular; microchannel plate; multiple electrode; sample injection; microchannel plates; microchannel array; injection directly; /204/205/239/
Citation Formats
Swierkowski, Stefan P. T-load microchannel array and fabrication method. United States: N. p., 2000.
Web.
Swierkowski, Stefan P. T-load microchannel array and fabrication method. United States.
Swierkowski, Stefan P. Sat .
"T-load microchannel array and fabrication method". United States. https://www.osti.gov/servlets/purl/873190.
@article{osti_873190,
title = {T-load microchannel array and fabrication method},
author = {Swierkowski, Stefan P},
abstractNote = {A three-dimensional (3-D) T-load for planar microchannel arrays for electrophoresis, for example, which enables sample injection directly onto a plane perpendicular to the microchannels' axis, at their ends. This is accomplished by forming input wells that extend beyond the ends of the microchannel thereby eliminating the right angle connection from the input well into the end of the microchannel. In addition, the T-load input well eases the placement of electrode in or adjacent the well and thus enables very efficient reproducible electrokinetic (ek) injection. The T-load input well eliminates the prior input well/microchannel alignment concerns, since the input well can be drilled after the top and bottom microchannel plates are bonded together. The T-load input well may extend partially or entirely through the bottom microchannel plate which enables more efficient gel and solution flushing, and also enables placement of multiple electrodes to assist in the ek sample injection.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {2000},
month = {1}
}