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Title: T-load microchannel array and fabrication method

Abstract

A three-dimensional (3-D) T-load for planar microchannel arrays for electrophoresis, for example, which enables sample injection directly onto a plane perpendicular to the microchannels' axis, at their ends. This is accomplished by forming input wells that extend beyond the ends of the microchannel thereby eliminating the right angle connection from the input well into the end of the microchannel. In addition, the T-load input well eases the placement of electrode in or adjacent the well and thus enables very efficient reproducible electrokinetic (ek) injection. The T-load input well eliminates the prior input well/microchannel alignment concerns, since the input well can be drilled after the top and bottom microchannel plates are bonded together. The T-load input well may extend partially or entirely through the bottom microchannel plate which enables more efficient gel and solution flushing, and also enables placement of multiple electrodes to assist in the ek sample injection.

Inventors:
 [1]
  1. Livermore, CA
Issue Date:
Research Org.:
Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States)
OSTI Identifier:
873190
Patent Number(s):
6110332
Assignee:
Regents of University of California (Oakland, CA)
DOE Contract Number:  
W-7405-ENG-48
Resource Type:
Patent
Country of Publication:
United States
Language:
English
Subject:
t-load; microchannel; array; fabrication; method; three-dimensional; 3-d; planar; arrays; electrophoresis; example; enables; sample; injection; directly; plane; perpendicular; microchannels; axis; accomplished; forming; input; extend; eliminating; angle; connection; addition; eases; placement; electrode; adjacent; efficient; reproducible; electrokinetic; ek; eliminates; prior; alignment; concerns; drilled; top; bottom; plates; bonded; partially; entirely; plate; solution; flushing; multiple; electrodes; assist; channel plate; multiple electrodes; fabrication method; plane perpendicular; microchannel plate; multiple electrode; sample injection; microchannel plates; microchannel array; injection directly; /204/205/239/

Citation Formats

Swierkowski, Stefan P. T-load microchannel array and fabrication method. United States: N. p., 2000. Web.
Swierkowski, Stefan P. T-load microchannel array and fabrication method. United States.
Swierkowski, Stefan P. Sat . "T-load microchannel array and fabrication method". United States. https://www.osti.gov/servlets/purl/873190.
@article{osti_873190,
title = {T-load microchannel array and fabrication method},
author = {Swierkowski, Stefan P},
abstractNote = {A three-dimensional (3-D) T-load for planar microchannel arrays for electrophoresis, for example, which enables sample injection directly onto a plane perpendicular to the microchannels' axis, at their ends. This is accomplished by forming input wells that extend beyond the ends of the microchannel thereby eliminating the right angle connection from the input well into the end of the microchannel. In addition, the T-load input well eases the placement of electrode in or adjacent the well and thus enables very efficient reproducible electrokinetic (ek) injection. The T-load input well eliminates the prior input well/microchannel alignment concerns, since the input well can be drilled after the top and bottom microchannel plates are bonded together. The T-load input well may extend partially or entirely through the bottom microchannel plate which enables more efficient gel and solution flushing, and also enables placement of multiple electrodes to assist in the ek sample injection.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {2000},
month = {1}
}

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