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Title: Micro-sonicator for spore lysis

Abstract

A micro-sonicator for spore lysis. Using micromachining technology, the micro-sonicator uses ultrasonic excitation of spores to perform spore and cell lysis. The micro-sonicator comprises a container with a cavity therein for retaining the sample in an ultrasonic transmission medium, the cavity being closed by a silicon membrane to which an electrode and piezoelectric material are attached, with the electrode and piezoelectric material being electrically connected to an AC signal generator which causes the membrane to flex and vibrate at the frequency of the applied voltage.

Inventors:
 [1];  [2];  [1]
+ Show Inventor Affiliations
  1. Livermore, CA
  2. Manteca, CA
Issue Date:
Research Org.:
Lawrence Livermore National Laboratory (LLNL), Livermore, CA (United States)
OSTI Identifier:
873141
Patent Number(s):
6100084
Assignee:
Regents of University of California (Oakland, CA)
Patent Classifications (CPCs):
C - CHEMISTRY C12 - BIOCHEMISTRY C12M - APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY
Y - NEW / CROSS SECTIONAL TECHNOLOGIES Y10 - TECHNICAL SUBJECTS COVERED BY FORMER USPC Y10S - TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
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DOE Contract Number:  
W-7405-ENG-48
Resource Type:
Patent
Country of Publication:
United States
Language:
English
Subject:
micro-sonicator; spore; lysis; micromachining; technology; ultrasonic; excitation; spores; perform; cell; comprises; container; cavity; therein; retaining; sample; transmission; medium; closed; silicon; membrane; electrode; piezoelectric; material; attached; electrically; connected; signal; generator; causes; flex; vibrate; frequency; applied; voltage; electrically connected; signal generator; transmission medium; applied voltage; piezoelectric material; cavity therein; ultrasonic transmission; spore lysis; /435/241/366/

Citation Formats

Miles, Robin R, Belgrader, Phillip, and Nasarabadi, Shanavaz L. Micro-sonicator for spore lysis. United States: N. p., 2000. Web.
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Miles, Robin R, Belgrader, Phillip, & Nasarabadi, Shanavaz L. Micro-sonicator for spore lysis. United States.
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Miles, Robin R, Belgrader, Phillip, and Nasarabadi, Shanavaz L. Sat . "Micro-sonicator for spore lysis". United States. https://www.osti.gov/servlets/purl/873141.
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@article{osti_873141,
title = {Micro-sonicator for spore lysis},
author = {Miles, Robin R and Belgrader, Phillip and Nasarabadi, Shanavaz L},
abstractNote = {A micro-sonicator for spore lysis. Using micromachining technology, the micro-sonicator uses ultrasonic excitation of spores to perform spore and cell lysis. The micro-sonicator comprises a container with a cavity therein for retaining the sample in an ultrasonic transmission medium, the cavity being closed by a silicon membrane to which an electrode and piezoelectric material are attached, with the electrode and piezoelectric material being electrically connected to an AC signal generator which causes the membrane to flex and vibrate at the frequency of the applied voltage.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {2000},
month = {1}
}
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