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Title: Boron-containing amino carboxylic acid compounds and uses thereof

Abstract

Novel compounds which are useful for boron neutron capture therapy (BNCT) are disclosed. The compounds comprise a stable boron-containing group and an aminocycloalkane carboxylic acid group or a boronated acyclic hydrocarbon-linked amino carboxylic acid. Methods for synthesis of the compounds and for use of the compounds in BNCT are disclosed.

Inventors:
 [1];  [1]
  1. (Knoxville, TN)
Issue Date:
Research Org.:
Univ. of Tennessee, Knoxville, TN (United States)
OSTI Identifier:
872909
Patent Number(s):
6037490
Application Number:
08/923,054
Assignee:
University of Tennessee Research Corporation (Knoxville, TN) ORO
DOE Contract Number:  
FG05-93ER61610
Resource Type:
Patent
Country of Publication:
United States
Language:
English
Subject:
boron-containing; amino; carboxylic; acid; compounds; novel; useful; boron; neutron; capture; therapy; bnct; disclosed; comprise; stable; aminocycloalkane; boronated; acyclic; hydrocarbon-linked; methods; synthesis; neutron capture; boron neutron; carboxylic acid; capture therapy; novel compounds; acid compounds; acid compound; containing amino; compounds comprise; novel compound; /999/

Citation Formats

Kabalka, George W., and Srivastava, Rajiv R. Boron-containing amino carboxylic acid compounds and uses thereof. United States: N. p., 2000. Web.
Kabalka, George W., & Srivastava, Rajiv R. Boron-containing amino carboxylic acid compounds and uses thereof. United States.
Kabalka, George W., and Srivastava, Rajiv R. Tue . "Boron-containing amino carboxylic acid compounds and uses thereof". United States. https://www.osti.gov/servlets/purl/872909.
@article{osti_872909,
title = {Boron-containing amino carboxylic acid compounds and uses thereof},
author = {Kabalka, George W. and Srivastava, Rajiv R.},
abstractNote = {Novel compounds which are useful for boron neutron capture therapy (BNCT) are disclosed. The compounds comprise a stable boron-containing group and an aminocycloalkane carboxylic acid group or a boronated acyclic hydrocarbon-linked amino carboxylic acid. Methods for synthesis of the compounds and for use of the compounds in BNCT are disclosed.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {2000},
month = {3}
}

Patent:

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