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Title: Three-dimensional scanning confocal laser microscope

Abstract

A confocal microscope for generating an image of a sample includes a first scanning element for scanning a light beam along a first axis, and a second scanning element for scanning the light beam at a predetermined amplitude along a second axis perpendicular to the first axis. A third scanning element scans the light beam at a predetermined amplitude along a third axis perpendicular to an imaging plane defined by the first and second axes. The second and third scanning element are synchronized to scan at the same frequency. The second and third predetermined amplitudes are percentages of their maximum amplitudes. A selector determines the second and third predetermined amplitudes such that the sum of the percentages is equal to one-hundred percent.

Inventors:
; ;
Issue Date:
Research Org.:
General Hospital Corp., Boston, MA (United States)
Sponsoring Org.:
USDOE
OSTI Identifier:
872718
Patent Number(s):
5995283
Application Number:
09/190,689
Assignee:
General Hospital Corporation (Boston, MA)
Patent Classifications (CPCs):
G - PHYSICS G02 - OPTICS G02B - OPTICAL ELEMENTS, SYSTEMS, OR APPARATUS
DOE Contract Number:  
FG02-91ER61229
Resource Type:
Patent
Resource Relation:
Patent File Date: 1998 Nov 12
Country of Publication:
United States
Language:
English
Subject:
/359/

Citation Formats

Anderson, R. Rox, Webb, Robert H., and Rajadhyaksha, Milind. Three-dimensional scanning confocal laser microscope. United States: N. p., 1999. Web.
Anderson, R. Rox, Webb, Robert H., & Rajadhyaksha, Milind. Three-dimensional scanning confocal laser microscope. United States.
Anderson, R. Rox, Webb, Robert H., and Rajadhyaksha, Milind. Fri . "Three-dimensional scanning confocal laser microscope". United States. https://www.osti.gov/servlets/purl/872718.
@article{osti_872718,
title = {Three-dimensional scanning confocal laser microscope},
author = {Anderson, R. Rox and Webb, Robert H. and Rajadhyaksha, Milind},
abstractNote = {A confocal microscope for generating an image of a sample includes a first scanning element for scanning a light beam along a first axis, and a second scanning element for scanning the light beam at a predetermined amplitude along a second axis perpendicular to the first axis. A third scanning element scans the light beam at a predetermined amplitude along a third axis perpendicular to an imaging plane defined by the first and second axes. The second and third scanning element are synchronized to scan at the same frequency. The second and third predetermined amplitudes are percentages of their maximum amplitudes. A selector determines the second and third predetermined amplitudes such that the sum of the percentages is equal to one-hundred percent.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {1999},
month = {1}
}

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Works referenced in this record:

Scanning Laser Ophthalmoscope
journal, July 1981


Morphometry of human epidermis in vivo by real-time confocal microscopy
journal, November 1993


Optics for laser rasters
journal, January 1984


Confocal scanning laser ophthalmoscope
journal, January 1987


The Optics of Human Skin
journal, July 1981


Flying spot TV ophthalmoscope
journal, January 1980


In vivo Vision of the Human Skin with the Tandem Scanning Microscope
journal, January 1993